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# Galaxy Code Architecture
John Chilton
Björn Grüning
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??? Presenter notes contain extra information which might be useful if you intend to use these slides for teaching. Press `P` again to switch presenter notes off Press `C` to create a new window where the same presentation will be displayed. This window is linked to the main window. Changing slides on one will cause the slide to change on the other. Useful when presenting. --- ### <i class="far fa-question-circle" aria-hidden="true"></i><span class="visually-hidden">question</span> Questions - How is the Galaxy code structured? - What do the various other projects related to Galaxy do? - What happens when I start Galaxy? --- ### <i class="fas fa-bullseye" aria-hidden="true"></i><span class="visually-hidden">objectives</span> Objectives - Explore various aspects of the Galaxy codebase. - Understand the various top-level files and modules in Galaxy. - Understand how dependencies work in Galaxy's frontend and backend. --- layout: true name: left-aligned class: left, middle --- layout: true class: center, middle --- layout: introduction_slides topic_name: Galaxy Architecture # Galaxy Architecture --- ### Please Interrupt! We're here to answer your questions about Galaxy architecture! --- class: enlarge200 **Chat:** [galaxyproject Lobby](https://matrix.to/#/#galaxyproject_Lobby:gitter.im) **GitHub:** [github.com/galaxyproject ](https://github.com/galaxyproject) **Twitter:** #usegalaxy, @galaxyproject --- ## The **/galaxyproject** projects *The architecture of the ecosystem.* ??? Too many to cover all but we'll cover some of the big ones in a few big categories. User-facing applications, projects for Galaxy plugin developers, and projects for Galaxy administrators. --- # Lots of Gitter actually ![galaxyproject gitter landing](../../images/gitter_galaxyproject.png) https://gitter.im/galaxyproject --- More links we'll mention as we go through the slides: - https://matrix.to/#/#galaxyproject_Lobby:gitter.im - https://matrix.to/#/#galaxyproject_dev:gitter.im - https://matrix.to/#/#galaxyproject_admins:gitter.im - https://matrix.to/#/#galaxyproject_FederatedGalaxy:gitter.im - https://matrix.to/#/#galaxyproject_bioblend:gitter.im - https://matrix.to/#/#galaxyproject_ephemeris:gitter.im - https://matrix.to/#/#usegalaxy-eu_Lobby:gitter.im - https://matrix.to/#/#galaxy-iuc_iuc:gitter.im - https://matrix.to/#/#bgruening_docker-galaxy-stable:gitter.im - https://matrix.to/#/#Galaxy-Training-Network_Lobby:gitter.im - https://matrix.to/#/#biocontainers_Lobby:gitter.im - https://matrix.to/#/#bioconda_Lobby:gitter.im Working group chats linked at https://galaxyproject.org/community/wg/. --- class: enlarge200 **User-Facing Applications** --- class: enlarge150 [galaxyproject/**galaxy** ](https://github.com/galaxyproject/galaxy) The main Galaxy application. Web interface, database model, job running, etc... Also includes other web applications including the **ToolShed**. --- class: enlarge150 [galaxyproject/**cloudlaunch** ](https://github.com/galaxyproject/cloudlaunch) CloudLaunch web application to make it easy to launch images on a cloud, drives *https://launch.usegalaxy.org* --- class: enlarge150 [galaxyproject/**training-material** ](https://github.com/galaxyproject/training-material) ![logo](/training-material/assets/images/GTNLogo1000.png) Galaxy training material for scientists, developers, and admins. Powers *https://training.galaxyproject.org/*. --- class: enlarge150 [galaxyproject/**hub** ](https://github.com/galaxyproject/galaxy-hub) The Galaxy Hub is the community and documentation hub for the Galaxy Project. It is maintained by the community through this GitHub repository. It is a static website built using the metalsmith static site generator. Powers *https://galaxyproject.org/*. --- class: enlarge150 [galaxyproject/**bioblend** ](https://github.com/galaxyproject/bioblend) Official Python client for the Galaxy, ToolShed, and CloudMan APIs. Best documented path to scripting the Galaxy API. --- class: enlarge150 - [galaxyproject/**blend4php**](https://github.com/galaxyproject/blend4php) - [galaxyproject/**blend4j**](https://github.com/galaxyproject/blend4j) - [**chapmanb/clj-blend**](https://github.com/chapmanb/clj-blend) Galaxy API bindings for other languages, less actively maintained. --- class: enlarge150 [galaxyproject/**cloudman**](https://github.com/galaxyproject/cloudman) Galaxy CloudMan - a web application which manages a Galaxy Kubernetes cluster in the cloud. --- class: enlarge150 [**bgruening/docker-galaxy-stable** ](https://github.com/bgruening/docker-galaxy-stable) High quality Docker containers for stable Galaxy environments. Releases corresponding to each new version of Galaxy. Many flavors available. --- class: white ![Docker](../../images/docker-chart.png) --- class: enlarge200 **For Plugin Developers** --- [galaxyproject/**tools-iuc** ](https://github.com/galaxyproject/tools-iuc) Galaxy tools maintained by the *IUC* ("Intergalactic Utilities Commission"). A variety of tools, generally of high quality including many of the core tools for Galaxy main. Demonstrates *current tool development best practices* - development on github and then deployed to test/main ToolSheds [galaxyproject/**tools-devteam** ](https://github.com/galaxyproject/tools-devteam) Many older tools appearing on usegalaxy.org. --- ### Tools Aside - More Repositories Other repositories with high quality tools: * [Björn Grüning's repo](https://github.com/bgruening/galaxytools) * Peter Cock's repos: * [blast repo](https://github.com/peterjc/galaxy_blast) * [pico repo](https://github.com/peterjc/pico_galaxy) * [mira repo](https://github.com/peterjc/galaxy_mira) * [ENCODE tools](https://github.com/modENCODE-DCC/Galaxy) * [Biopython repo](https://github.com/biopython/galaxy_packages) * [Galaxy Proteomics repo](https://github.com/galaxyproteomics/tools-galaxyp) * [Greg von Kuster's repo](https://github.com/gregvonkuster/galaxy-csg) * [TGAC repo](https://github.com/TGAC/tgac-galaxytools) * [AAFC-MBB Canada repo](https://github.com/AAFC-MBB/Galaxy/tree/master/wrappers) * [Mark Einon's repo](https://gitlab.com/einonm/galaxy-tools) --- [galaxyproject/**iwc** ](https://github.com/galaxyproject/iwc) Intergalactic Workflow Commission. Hosting workflows and defining best practices for publishing workflows. https://matrix.to/#/#galaxyproject_iwc:gitter.im --- class: enlarge150 [galaxyproject/**planemo** ](https://github.com/galaxyproject/planemo) Command-line utilities to assist in the development of Galaxy tools and workflows. Linting, testing, deploying to ToolSheds... *The best practice approach for Galaxy tool development!* [galaxyproject/**planemo-machine** ](https://github.com/galaxyproject/planemo-machine) Builds Galaxy environments for Galaxy tool development including Docker container, virtual machines, Google compute images --- [galaxyproject/**galaxy-language-server** ](https://github.com/galaxyproject/galaxy-language-server) ![Galaxy Language Server](https://github.com/galaxyproject/galaxy-language-server/raw/assets/snippets.gif) Language server implementation for Galaxy tools. Visual Studio Code extension for tool development. Test execution, code completion, best practices, documentation tooltips, etc.. --- class: enlarge150 [galaxyproject/**starforge** ](https://github.com/galaxyproject/starforge) ![StarForge logo](https://raw.githubusercontent.com/galaxyproject/starforge/master/docs/starforge_logo.png) Build Galaxy framework dependencies as Python wheels when needed. --- class: enlarge150 [galaxyproject/**cargo-port** ](https://github.com/galaxyproject/cargo-port) ![Cargo Port Logo](https://raw.githubusercontent.com/galaxyproject/cargo-port/master/media/cpc-plain-small.png) Provides stable URLs and caching for application links, etc.. An important layer for reproducibility but largely transparent. --- class: enlarge200 **For Deployers and Admins** --- class: enlarge150 galaxyproject/**{ansible-\*, \*-playbook}**<br> usegalaxy-eu/**{ansible-\*, \*-playbook}** [Ansible](https://www.ansible.com/) components to automate almost every aspect of Galaxy installation and maintenance. Ansible is an advanced configuration management system These playbooks are used to maintain Galaxy main, cloud and Docker images, virtual machines, ... --- class: enlarge150 [galaxyproject/**gravity** ](https://github.com/galaxyproject/gravity) A process manager (supervisor) and management tools for Galaxy servers. `galaxyctl` which is used to manage the starting, stopping, and logging of Galaxy's various processes. `galaxy` which can be used to run a Galaxy server in the foreground. --- class: enlarge150 [galaxyproject/**galaxy-helm** ](https://github.com/galaxyproject/galaxy-helm) Kubernetes helm chart for deploying Galaxy. Leveraged by cloudlaunch and CloudMan but usable standalone. --- class: enlarge150 [galaxyproject/**pulsar** ](https://github.com/galaxyproject/pulsar) ![Pulsar Logo](https://galaxyproject.org/images/galaxy-logos/pulsar_transparent.png) Distributed job execution engine for Galaxy. Stages data, scripts, configuration. Can run jobs on Windows machines. Can act as its own queuing system or access an existing cluster DRM. --- class: enlarge150 [galaxyproject/**ephemeris** ](https://github.com/galaxyproject/ephemeris) Library and CLI for managing Galaxy plugins - tools, index data, and workflows. Layer on top of BioBlend building useful utilities for working with the Galaxy API from an administrator perspective. --- class: enlarge150 [galaxyproject/**gxadmin** ](https://github.com/galaxyproject/gxadmin) Handy command-line utility for Galaxy administrators. --- class: enlarge150 ### ephemeris vs gxadmin Ephemeris generally talks to the Galaxy API and is a pure Python project, gxadmin talks directly to the Galaxy database and relevant files. --- ### Total Perspective Vortex [galaxyproject/total-perspective-vortex **](https://github.com/galaxyproject/total-perspective-vortex) ![TPV Logo](https://raw.githubusercontent.com/galaxyproject/total-perspective-vortex/main/docs/images/tpv-logo-wide.png) TotalPerspectiveVortex (TPV) provides an installable set of dynamic rules for the Galaxy application that can route entities (Tools, Users, Roles) to appropriate job destinations based on a configurable yaml file. --- class: enlarge150 [**usegalaxy-eu/tiaas2 **](https://github.com/usegalaxy-eu/tiaas2) ![TIAAS Logo](https://raw.githubusercontent.com/usegalaxy-eu/tiaas2/master/images/tiaas-logo.png) Django-based infrastructure for creating pools of users, etc.. for training events and connecting them to Galaxy. --- ### Some (out of many) friends of the project ![Bioconda](../../../../shared/images/conda_logo.png) ![Biocontainers](../../images/biocontainers.png) Check out dev training materials "Tool Dependencies and Conda" and "Tool Dependencies and Containers" for more context. --- ## Putting it all together ![Large graphic showing different domains and where different portions of the Galaxy community can be found from Biology, Dev, Packaging, Deployment, Documentation, Training, and Support.](../../images/galaxy_main_scheme.png) ??? TODO: cover gxformat2 --- class: enlarge200 [galaxyproject/**galaxy** ](https://github.com/galaxyproject/galaxy) The rest of the slides will focus on the core repository. --- ## Project Management *The social architecture of the project.* --- class: enlarge200 ### Contributing Quick Start Contribution guidelines: https://bit.ly/gx-CONTRIBUTING-md --- class: enlarge200 ### Pull Requests Nearly all changes should come in through GitHub Pull Requests. The exceptions include security patches, packaging and release process artifacts, and backporting fixes to older releases. --- class: enlarge150 ### Security (SECURITY_POLICY.md) In brief, to responsibly report security issues e-mail [`galaxy-committers@lists.galaxyproject.org`](mailto:galaxy-committers@lists.galaxyproject.org) Check out the full policy in [SECURITY_POLICY.md](https://github.com/galaxyproject/galaxy/blob/dev/SECURITY_POLICY.md). --- ### Branches ![Branches](../../images/core_branches.plantuml.svg) --- class: enlarge150 ### Committers & Open Goverance All repository goverance is done in the open on GitHub via Pull Requests and voting. Galaxy goes beyond open source to open goverance. > "The committers group is the group of trusted developers and advocates who manage the core Galaxy code base." > "Galaxy Project committers are the only individuals who may commit to the core Galaxy code base." > "Committers may participate in all formal votes, including votes to modify team membership, merge pull requests, and modify [policies]." --- class: enlarge150 ### Working Groups https://galaxyproject.org/community/wg/ > "Galaxy has grown a lot over the years, going from a project at one university in 2005 to the global community it is today. Several parts of the Galaxy ecosystem have become avowedly and obviously community driven during that time, including tools, code, training, and several other international efforts. Galaxy Working Groups push this global model to other areas of Galaxy as well." --- class: enlarge200 ### Code of Conduct (CODE_OF_CONDUCT.md) Describes expectations, encourages diversity, and describes how to report issues such as unacceptable behavior. Check out the full policy in [CODE_OF_CONDUCT.md](https://github.com/galaxyproject/galaxy/blob/dev/CODE_OF_CONDUCT.md). --- class: enlarge150 ### Release Process New large releases are issued roughly every 4 months. The process is guided by an auto-created self documenting release issue. Check out the [21.05 release issue](https://github.com/galaxyproject/galaxy/issues/11770) as an example. Working groups create roadmaps aligned with each release and coordinated with project leadership. --- class: enlarge150 ### Organizing Issues and Pull Requests Extensive use of Github tags are used to try to organize the numerous issues and pull requests of the Galaxy repository. The tags are described in detail in [issues.rst](https://github.com/galaxyproject/galaxy/blob/dev/doc/source/project/issues.rst). --- ### Continuous Integration (CI) ![Galaxy CI](../../images/core_ci.png) If you get Red Xs - take a second to ponder whether they make sense and don't be afraid to ask, it is a complex system with a lot of noise! --- ### Linting and Code Formatting Part of the Galaxy CI process includes linting and checking the format of both the backend Python and frontend ES 6 code. This linting process captures many common problems as well as enforcing a common code style. The output reports from the CI process are relatively straightforward, but it is a good process to lint changes and formatting your code before opening pull requests for them. Execute the `format` make command to format the backend code and then use `tox` to lint the formatted code. ``` $ make format $ tox -e lint ``` Execute the `client-format` make command to format the code and then the `client-lint` command to lint the formatted code. ``` $ make client-format $ make client-lint ``` --- ### mypy and Python Types Starting with release 21.01, portions of the Galaxy backend have Python 3 type annotations and static checking is performed as part of CI. Imported library types are not enforcing and [mypy](https://mypy.readthedocs.io/en/stable/) does a fair job inferring types in most situations, so this process should be relatively transparent to contributors. If there are problems with typing, the CI produces explicit output about how to correct problems. These problems generally just require a single type annotation. Feel free to request help on a pull request for what that should look like. To run a subset of the python type checking locally, `tox` again can be used: ``` $ tox -e mypy ``` A quick overview about why to add type annotations to Python code and how to use them can be found on this [blog post](https://dev.to/dstarner/using-pythons-type-annotations-4cfe). Additional useful resources include [this cheat sheet from mypy](https://mypy.readthedocs.io/en/stable/cheat_sheet_py3.html) and the Python docs for the [typing module](https://docs.python.org/3/library/typing.html). --- class: enlarge200 ### Development Environments Galaxy developers use a wide range of IDEs and we don't offer any formal recommendation of one over another. However, Marius has assembled some documentation on debugging the [Galaxy server](https://docs.galaxyproject.org/en/master/dev/debugging_galaxy.html) and [tests](https://docs.galaxyproject.org/en/master/dev/debugging_tests.html) using VS Code. --- ### Development Environment - Gitpod Galaxy does have a Gitpod configuration that is enabled to allow editing and testing PRs https://www.gitpod.io/. Video from Marius presenting Gitpod at the Galaxy Developer Roundtable (https://www.youtube.com/watch?v=3e71DFg3gsw#t=39m0s) --- ### docs.galaxyproject.org ![docs.galaxyproject.org](../../images/core_docs.png) All these documents as well as versions code and deployment documentation and release notes can be found at [docs.galaxyproject.org](https://docs.galaxyproject.org). --- ## Principles *The guiding principles of the core code architecture.* --- ### Aspirational Principles of Galaxy Architecture Whereas the architecture of the frontend (Web UI) aims for consistency and is highly opinionated, the backend (Python server) is guided by flexibility and is meant to be driven by plugins whenever possible. ??? Though an imperfect abstraction... maybe it is beneficial to think of the organizational principles that guide frontend and backend development of Galaxy as diametrically opposite. The frontend architecture is guided by the principle that the end user experience should be as simple and consistent as possible. The backend has been deployed at so many different sites and targeting so many different technologies - that flexibility is paramount. --- ### An Opinionated Frontend - The target audience is a *bench scientist* - no knowledge of programming, paths, or command lines should be assumed. - Consistent colors, fonts, themes, etc... - Reusable components for presenting common widgets - from the generic (forms and grids) to the specific (tools and histories). - Tied to specific technologies: - Implemented in JavaScript (ES6) - Built with [webpack](https://webpack.js.org/) - [Vue.js](https://vuejs.org/) for component definitions --- ### A Plugin Driven Backend Galaxy's backend is in many ways driven by *pluggable interfaces* and can be adapted to many different technologies. - SQLAlchemy allows using SQLite, PostgreSQL, or MySQL (sort of) for your database. - Many different cluster backends or job managers are supported. - Different frontend proxies (e.g. nginx) are supported as well as web application containers (e.g. uWSGI, gunicorn). - Different storage strategies and technologies are supported (e.g. S3, iRODS). - Tool definitions, job metrics, stat middleware, tool dependency resolution, workflow modules, datatype definitions are all plugin driven. ??? If the chief architectural principle guiding the frontend is a fast and accessible experience for the bench scientist, perhaps for the backend it is allowing deployment on many different platforms and a different scales. --- ### A Plugin Driven Backend but... Galaxy has long been guided by the principle that cloning it and calling the `run.sh` should "just work" and should work quickly. So by default Galaxy does not require: - Compilation - it fetches *binary wheels* for your platform. - A job manager - Galaxy can act as one. - An external database server - Galaxy can use an sqlite database. - A web proxy or external Python web server. --- class: enlarge200 ### In other words... The Galaxy frontend is architected with the bench scientist in mind first and foremost, the Galaxy backend is architected with Galaxy administrators in mind first and foremost. ??? TODO: slide connecting architecture to people here --- ## Files and Directories *The physical architecture of the Galaxy code.* --- ### Project Docs ![Project Files](../../images/core_files_project_docs.plantuml.svg) --- ### Code ![Code](../../images/core_files_code.plantuml.svg) --- ### Scripts ![Scripts](../../images/core_files_scripts.plantuml.svg) --- ### Test Sources ![Test Source Files](../../images/core_files_test.plantuml.svg) --- ### Continuous Integration ![Continuous Integration Files](../../images/core_files_ci.plantuml.svg) --- ### One Repository, Two Views of a Project ![Two Views of Galaxy Python Project](../../images/core_files_code_python_2_views.plantuml.svg) `lib` contains a single monolithic view of the `galaxy` namespace. Each sub-directory of `packages` contains a logical subset of this `galaxy` namespace. Directory symbolic links are used to ensure the same files are used. ??? TODO: a slide before this one describing Python modules and how they map to files using galaxy.util, galaxy.model.mapping, and galaxy.web.framework. --- ### Package Structure ![package structure](../../images/core_packages.plantuml.svg) --- ### PyPI ![galaxy-tool-util on PyPI](../../images/core_tool_util_pypi.png) --- ![Package Files](../../images/core_files_code_package.plantuml.svg) --- ## Web Frameworks *The architecture of an interaction.* --- class: reduce70 ![Client-Server Communications](../../images/server_client_vuejs.plantuml.svg) Bits and pieces of older client technologies appear throughout - ranging from Python mako templates to generate HTML, lower-level jQuery, and lots of Backbone legacy MVC. --- ![Processing requests on the server](../../images/asgi_app.plantuml.svg) Expanding the right side of that diagram. We will move through the components left to right. --- class: enlarge120 template: left-aligned ### ASGI - Application Spiritual successor to [WSGI](https://www.python.org/dev/peps/pep-0333/). An ASGI application is an async callable that takes in a `scope` (`dict` describing the connection), `send` (an async callable to respond to events via), and `receive` (an async callable to receive messages). ```python async def application(scope, receive, send): event = await receive() ... await send({"type": "http.response.body", ...}) ``` Checkout [ASGI documentation](https://asgi.readthedocs.io/) for more details. --- template: left-aligned ### ASGI & Starlette Low-level Example We will talk a lot about Galaxy and FastAPI - but much of its plumbing is just aliases for starlette ASGI handling. ```python from starlette.responses import PlainTextResponse async def app(scope, receive, send): assert scope['type'] == "http" response = PlainTextResponse('Hello, world!') await response(scope, receive, send) ``` If this is placed in a file called `example.py` with Starlette on the Python path, the application server uvicorn can then host this application with the following shell command: ``` $ uvicorn example:app INFO: Started server process [11509] INFO: Uvicorn running on http://127.0.0.1:8000 (Press CTRL+C to quit) ``` Example from [starlette.io](https://www.starlette.io/). --- template: left-aligned ### ASGI - Starlette High-level Example Building a higher-level `example.py` with Starlette. ```python from starlette.applications import Starlette from starlette.responses import JSONResponse from starlette.routing import Route async def homepage(request): return JSONResponse({'hello': 'world'}) app = Starlette(debug=True, routes=[ Route('/', homepage), ]) ``` A small framework for building web applications. --- template: left-aligned ### ASGI - FastAPI From https://github.com/tiangolo/fastapi/blob/master/fastapi/applications.py ```python ... from starlette.applications import Starlette ... class FastAPI(Starlette): ... ``` FastAPI (the library and the application base) extends starlette framework with features for building APIs. These include data validation, serialization, documentation generation. --- ![Processing requests on the server](../../images/asgi_app.plantuml.svg) --- template: left-aligned ### FastAPI `__call__` https://github.com/tiangolo/fastapi/blob/master/fastapi/applications.py ```python async def __call__(self, scope: Scope, receive: Receive, send: Send) -> None: if self.root_path: scope["root_path"] = self.root_path if AsyncExitStack: async with AsyncExitStack() as stack: scope["fastapi_astack"] = stack await super().__call__(scope, receive, send) else: await super().__call__(scope, receive, send) # pragma: no cover ``` A light wrapper around Starlette's call entry point. --- template: left-aligned ### Starlette `__call__` https://github.com/encode/starlette/blob/master/starlette/applications.py ```python async def __call__(self, scope: Scope, receive: Receive, send: Send) -> None: scope["app"] = self await self.middleware_stack(scope, receive, send) ``` Walks through Starlette middleware. --- template: left-aligned ### Starlette `build_middleware_stack` https://github.com/encode/starlette/blob/master/starlette/applications.py ```python def build_middleware_stack(self) -> ASGIApp: ... app = self.router for cls, options in reversed(middleware): app = cls(app=app, **options) return app ``` Start with the router and surround it with each layer of configured middleware. --- template: left-aligned class: enlarge150 ### ASGI Middleware > It is possible to have ASGI “middleware” - code that plays the role of both server and application, taking in a scope and the send/receive awaitable callables, potentially modifying them, and then calling an inner application. https://asgi.readthedocs.io/en/latest/specs/main.html#middleware --- template: left-aligned class: enlarge150 ### Starlette Middleware > Starlette includes several middleware classes for adding behavior that is applied across your entire application. These are all implemented as standard ASGI middleware classes, and can be applied either to Starlette or to any other ASGI application. https://www.starlette.io/middleware/ --- template: left-aligned ### Starlette `build_middleware_stack` https://github.com/encode/starlette/blob/master/starlette/applications.py ```python def build_middleware_stack(self) -> ASGIApp: ... app = self.router for cls, options in reversed(middleware): app = cls(app=app, **options) return app ``` Notice the inner most layer is the router. --- template: left-aligned ### FastAPI Router Initialization https://github.com/tiangolo/fastapi/blob/master/fastapi/applications.py ```python class FastAPI(Starlette): def __init__(self, ...): self.router: routing.APIRouter = routing.APIRouter( routes=routes, ) ``` --- ### FastAPI Router ```python from starlette import routing class APIRouter(routing.Router): ... ``` --- ### Starlette Router https://github.com/encode/starlette/blob/master/starlette/routing.py ```python async def __call__(self, scope: Scope, receive: Receive, send: Send) -> None: ... for route in self.routes: # Determine if any route matches the incoming scope, # and hand over to the matching route if found. match, child_scope = route.matches(scope) if match == Match.FULL: scope.update(child_scope) await route.handle(scope, receive, send) return ... ``` https://www.starlette.io/routing/ --- ![Router Class Diagram](../../images/routers.plantuml.svg) - https://www.starlette.io/routing/ - https://fastapi.tiangolo.com/tutorial/bigger-applications/#apirouter - https://fastapi-utils.davidmontague.xyz/user-guide/inferring-router/ --- class: enlarge200 In order to understand how the routing classes are setup within Galaxy, lets step back and look really quickly at how Galaxy's FastAPI application (ASGI endpoint) is constructed. --- ### FastAPI Factory `lib/galaxy/webapps/galaxy/fast_factory.py` ```python def factory(): props = WebappSetupProps( app_name='galaxy', default_section_name=DEFAULT_CONFIG_SECTION, env_config_file='GALAXY_CONFIG_FILE', env_config_section='GALAXY_CONFIG_SECTION', check_galaxy_root=True ) config_provider = WebappConfigResolver(props) config = config_provider.resolve_config() gx_webapp, gx_app = app_pair( global_conf=config.global_conf, load_app_kwds=config.load_app_kwds, wsgi_preflight=config.wsgi_preflight ) return initialize_fast_app(gx_webapp, gx_app) ``` --- ### FastAPI Application `lib/galaxy/webapps/galaxy/fast_app.py` ```python def initialize_fast_app(gx_webapp, gx_app): app = FastAPI( title="Galaxy API", docs_url="/api/docs", openapi_tags=api_tags_metadata, ) add_exception_handler(app) add_galaxy_middleware(app, gx_app) add_request_id_middleware(app) include_all_package_routers(app, 'galaxy.webapps.galaxy.api') wsgi_handler = WSGIMiddleware(gx_webapp) app.mount('/', wsgi_handler) return app ``` --- ### Finding API Routers Following this line: `include_all_package_routers(app, 'galaxy.webapps.galaxy.api')` to the file `lib/galaxy/webapps/base/api.py` ```python def include_all_package_routers(app: FastAPI, package_name: str): for _, module in walk_controller_modules(package_name): router = getattr(module, "router", None) if router: app.include_router(router) ``` --- class: reduce70 ### Routing inside the Application ```python router = Router(tags=['tags']) @router.cbv class FastAPITags: manager: TagsManager = depends(TagsManager) @router.put( '/api/tags', summary="Apply a new set of tags to an item.", status_code=status.HTTP_204_NO_CONTENT, ) def update( self, trans: ProvidesUserContext = DependsOnTrans, payload: ItemTagsPayload = Body( ..., # Required title="Payload", description="Request body containing the item and the tags to be assigned.", ), ): """Replaces the tags associated with an item with the new ones specified in the payload. - The previous tags will be __deleted__. - If no tags are provided in the request body, the currently associated tags will also be __deleted__. """ self.manager.update(trans, payload) ``` --- ![Router Class Diagram](../../images/routers.plantuml.svg) - https://www.starlette.io/routing/ - https://fastapi.tiangolo.com/tutorial/bigger-applications/#apirouter - https://fastapi-utils.davidmontague.xyz/user-guide/inferring-router/ --- ### WSGI Fallback Back to `initialize_fast_app`, two of the final lines were as follows: ```python wsgi_handler = WSGIMiddleware(gx_webapp) app.mount('/', wsgi_handler) ``` This effectively provides a fallback to our legacy WSGI application. --- ### WSGI - Python interface for web servers defined by PEP 333 - https://www.python.org/dev/peps/pep-0333/. - Galaxy tends to favor uWSGI, but other options such as Gunicorn and Paste can be used to host the application. - https://uwsgi-docs.readthedocs.io/ (a million bells and whistles, highly performant, a bit brittle) - https://gunicorn.org/ (simpler, more standard Python 3 WSGI server) - https://bitbucket.org/ianb/paste (more of legacy interest, but still heavily used in testing for instance) --- ![Processing requests on the server](../../images/wsgi_app.plantuml.svg) --- template: left-aligned ### WSGI Middleware A WSGI function: `def app(environ, start_response):` - Middleware act as filters, modify the `environ` and then pass through to the next webapp - Galaxy uses several middleware components defined in the `wrap_in_middleware` function of `galaxy.webapps.galaxy.buildapp`. --- template: left-aligned ### Galaxy's WSGI Middleware Middleware configured in `galaxy.webapps.galaxy.buildapp#wrap_in_middleware`. - `paste.httpexceptions#make_middleware` - `galaxy.web.framework.middleware.remoteuser#RemoteUser` (if configured) - `paste.recursive#RecursiveMiddleware` - `galaxy.web.framework.middleware.sentry#Sentry` (if configured) - Various debugging middleware (linting, interactive exceptions, etc...) - `galaxy.web.framework.middleware.statsd#StatsdMiddleware` (if configured) - `galaxy.web.framework.middleware.xforwardedhost#XForwardedHostMiddleware` - `galaxy.web.framework.middleware.request_id#RequestIDMiddleware` --- ![Processing requests on the server (WSGI)](../../images/wsgi_app.plantuml.svg) --- ### Instances ![webapp](../../images/webapp.plantuml.svg) --- ### Classes ![GalaxyWebApplication class diagram](../../images/webapp_classes.plantuml.svg) --- template: left-aligned ### Routes Setup on `webapp` in `galaxy.webapps.galaxy.buildapp.py`. ```python webapp.add_route( '/datasets/:dataset_id/display/{filename:.+?}', controller='dataset', action='display', dataset_id=None, filename=None ) ``` URL `/datasets/278043/display` matches this route, so `handle_request` will - lookup the controller named “dataset” - look for a method named “display” that is exposed - call it, passing dataset_id and filename as keyword arg Uses popular Routes library (https://pypi.python.org/pypi/Routes). --- template: left-aligned Simplified `handle_request` from `lib/galaxy/web/framework/base.py`. ```python def handle_request(self, environ, start_response): path_info = environ.get( 'PATH_INFO', '' ) map = self.mapper.match( path_info, environ ) if path_info.startswith('/api'): controllers = self.api_controllers else: controllers = self.controllers trans = self.transaction_factory( environ ) controller_name = map.pop( 'controller', None ) controller = controllers.get( controller_name, None ) # Resolve action method on controller action = map.pop( 'action', 'index' ) method = getattr( controller, action, None ) kwargs = trans.request.params.mixed() # Read controller arguments from mapper match kwargs.update( map ) body = method( trans, **kwargs ) # Body may be a file, string, etc... respond with it. ``` --- class: enlarge150 ### Controllers Three varieties 1. FastAPI ASGI API controllers 2. WSGI API controllers 3. Legacy WSGI web controllers. Ideally each of these are *thin*. Focused on "web things" - adapting parameters and responses and move "business logic" to components not bound to web functionality. --- class: enlarge150 ### FastAPI Controllers - Found in `lib/galaxy/webapps/galaxy/controllers/api/`. - Consume and produce typed data using Python 3 type annotations, FastAPI helpers, and Pydantic models. - Router specifies HTTP verb (GET, POST, PUT, etc..) and how to parse path. --- class: reduce70 ### FastAPI Controller Example `lib/galaxy/webapps/galaxy/controllers/api/roles.py` ```python @router.cbv class FastAPIRoles: role_manager: RoleManager = depends(RoleManager) @router.get('/api/roles') def index(self, trans: ProvidesUserContext = DependsOnTrans) -> RoleListModel: roles = self.role_manager.list_displayable_roles(trans) return RoleListModel(__root__=[role_to_model(trans, r) for r in roles]) @router.get('/api/roles/{id}') def show(self, id: EncodedDatabaseIdField, trans: ProvidesUserContext = DependsOnTrans) -> RoleModel: role_id = trans.app.security.decode_id(id) role = self.role_manager.get(trans, role_id) return role_to_model(trans, role) @router.post("/api/roles", require_admin=True) def create(self, trans: ProvidesUserContext = DependsOnTrans, role_definition_model: RoleDefinitionModel = Body(...)) -> RoleModel: role = self.role_manager.create_role(trans, role_definition_model) return role_to_model(trans, role) ``` --- class: reduce70 ### FastAPI and Pydantic ```python RoleIdField = Field(title="ID", description="Encoded ID of the role") RoleNameField = Field(title="Name", description="Name of the role") RoleDescriptionField = Field(title="Description", description="Description of the role") class BasicRoleModel(BaseModel): id: EncodedDatabaseIdField = RoleIdField name: str = RoleNameField type: str = Field(title="Type", description="Type or category of the role") class RoleModel(BasicRoleModel): description: str = RoleDescriptionField url: str = Field(title="URL", description="URL for the role") model_class: str = Field(title="Model class", description="Database model class (Role)") class RoleDefinitionModel(BaseModel): name: str = RoleNameField description: str = RoleDescriptionField user_ids: Optional[List[EncodedDatabaseIdField]] = Field(title="User IDs", default=[]) group_ids: Optional[List[EncodedDatabaseIdField]] = Field(title="Group IDs", default=[]) ``` --- ### FastAPI and OpenAPI `FastAPI(title="Galaxy API", docs_url="/api/docs", ...)` ![OpenAPI Docs from FastAPI at api/docs](../../images/core_api_docs.png) --- ![OpenAPI Docs from FastAPI at api/docs for roles](../../images/core_api_docs_roles.png) --- class: enlarge150 ### WSGI API Controllers - Also in `lib/galaxy/webapps/galaxy/controllers/api/` - Mirroring FastAPI controllers until FastAPI required (likely 21.09) - Exposed method take `trans` and request parameters and return a JSON response (possibly including Pydantic objects) --- class: reduce70 ### WSGI API Controller Example `lib/galaxy/webapps/galaxy/controllers/api/roles.py` ```python class RoleAPIController(BaseGalaxyAPIController): role_manager: RoleManager = depends(RoleManager) @web.expose_api def index(self, trans: ProvidesUserContext, **kwd): """ GET /api/roles Displays a collection (list) of roles. """ roles = self.role_manager.list_displayable_roles(trans) return RoleListModel(__root__=[role_to_model(trans, r) for r in roles]) @web.expose_api def show(self, trans: ProvidesUserContext, id: str, **kwd): """ GET /api/roles/{encoded_role_id} Displays information about a role. """ role_id = decode_id(self.app, id) role = self.role_manager.get(trans, role_id) return role_to_model(trans, role) @web.expose_api @web.require_admin def create(self, trans: ProvidesUserContext, payload, **kwd): """ POST /api/roles Creates a new role. """ expand_json_keys(payload, ["user_ids", "group_ids"]) role_definition_model = RoleDefinitionModel(**payload) role = self.role_manager.create_role(trans, role_definition_model) return role_to_model(trans, role) ``` --- class: enlarge150 ### Legacy WSGI Controllers - `lib/galaxy/webapps/galaxy/controllers/` - Return arbitrary content - JSON, HTML, etc... - Render HTML components using [mako](http://www.makotemplates.org/) templates (see `templates/`) - The usage of these should continue to decrease over time. --- ## `app` and Dependency Injection *The architecture of connecting Galaxy components.* --- ![Big Interconnected App Python 2](../../images/app_py2.plantuml.svg) --- ### A God object > "a God object is an object that knows too much or does too much. The God object is an example of an anti-pattern and a code smell." https://en.wikipedia.org/wiki/God_object Not only does `app` know and do too much, it is also used way too many places. Every interesting component, every controller, the web transaction, etc.. has a reference to `app`. --- ### A Typical Usage ```python class DatasetCollectionManager: def __init__(self, app): self.type_registry = DATASET_COLLECTION_TYPES_REGISTRY self.collection_type_descriptions = COLLECTION_TYPE_DESCRIPTION_FACTORY self.model = app.model self.security = app.security self.hda_manager = hdas.HDAManager(app) self.history_manager = histories.HistoryManager(app) self.tag_handler = tags.GalaxyTagHandler(app.model.context) self.ldda_manager = lddas.LDDAManager(app) ``` --- ![Big Interconnected App Python 3 - no right](../../images/app_types_no_interface.plantuml.svg) --- ## Problematic Dependency Graph ```python class DatasetCollectionManager: def __init__(self, app: UniverseApplication): self.type_registry = DATASET_COLLECTION_TYPES_REGISTRY self.collection_type_descriptions = COLLECTION_TYPE_DESCRIPTION_FACTORY self.model = app.model self.security = app.security self.hda_manager = hdas.HDAManager(app) self.history_manager = histories.HistoryManager(app) self.tag_handler = tags.GalaxyTagHandler(app.model.context) self.ldda_manager = lddas.LDDAManager(app) ``` `UniverseApplication` creates a `DatasetCollectionManager` for the application and `DatasetCollectionManager` imports and annotates the `UniverseApplication` as a requirement. This creates an unfortunate dependency loop. **Dependencies should form a DAG (directed acyclic graph)**. --- ![Big Interconnected App with Python 3 Types](../../images/app_types.plantuml.svg) --- ## Why an Interface? Dependencies now closer to a DAG - `DatasetCollectionManager` no longer annotated with the type `UniverseApplication`! Imports are cleaner. --- ## Benefits of Typing ```python class DatasetCollectionManager: def __init__(self, app: StructuredApp): self.type_registry = DATASET_COLLECTION_TYPES_REGISTRY self.collection_type_descriptions = COLLECTION_TYPE_DESCRIPTION_FACTORY self.model = app.model self.security = app.security self.hda_manager = hdas.HDAManager(app) self.history_manager = histories.HistoryManager(app) self.tag_handler = tags.GalaxyTagHandler(app.model.context) self.ldda_manager = lddas.LDDAManager(app) ``` - mypy provides robust type checking. - IDE can provide hints to make developing this class and usage of this class easier. --- class: reduce90 ### Design Problems with Handling Dependencies Directly Using app to construct a manager for dealing with dataset collections. ```python class DatasetCollectionManager: def __init__(self, app: StructuredApp): self.type_registry = DATASET_COLLECTION_TYPES_REGISTRY self.collection_type_descriptions = COLLECTION_TYPE_DESCRIPTION_FACTORY self.model = app.model self.security = app.security self.hda_manager = hdas.HDAManager(app) self.history_manager = histories.HistoryManager(app) self.tag_handler = tags.GalaxyTagHandler(app.model.context) self.ldda_manager = lddas.LDDAManager(app) ``` - DatasetCollectionManager needs to know how to construct all the other managers it is using, not just their interface. - `app` has a instance of this class and `app` is used to construct and instance of this class - this circular dependency chain results in brittleness and complexity in how to construct `app`. - `app` is very big and we're depending on a lot of it but not a large percent it. This makes typing less than ideal. --- class: reduce90 ### Testing Problems with Handling Dependencies Directly ```python class DatasetCollectionManager: def __init__(self, app: StructuredApp): self.type_registry = DATASET_COLLECTION_TYPES_REGISTRY self.collection_type_descriptions = COLLECTION_TYPE_DESCRIPTION_FACTORY self.model = app.model self.security = app.security self.hda_manager = hdas.HDAManager(app) self.history_manager = histories.HistoryManager(app) self.tag_handler = tags.GalaxyTagHandler(app.model.context) self.ldda_manager = lddas.LDDAManager(app) ``` - Difficult to unit test properly - What parts of app are being used? - How do we construct a smaller app with just those pieces? - How do we stub out classes cleanly when we're creating the dependent objects internally. --- class: reduce90 ### Design Benefits of Injecting Dependencies .code[```python class DatasetCollectionManager: def __init__( self, model: GalaxyModelMapping, security: IdEncodingHelper, hda_manager: HDAManager, history_manager: HistoryManager, tag_handler: GalaxyTagHandler, ldda_manager: LDDAManager, ): self.type_registry = DATASET_COLLECTION_TYPES_REGISTRY self.collection_type_descriptions = COLLECTION_TYPE_DESCRIPTION_FACTORY self.model = model self.security = security self.hda_manager = hda_manager self.history_manager = history_manager self.tag_handler = tag_handler self.ldda_manager = ldda_manager ```] - We're no longer depending on `app`. - The type signature very clearly delineates what dependencies are required. - Unit testing can inject precise dependencies supplying only the behavior needed. --- ### Constructing the Object Is Still Brittle ```python DatasetCollectionManager( self.model, self.security, HDAManager(self), HistoryManager(self), GalaxyTagHandler(self.model.context), LDDAManager(self) ) ``` - The complexity in ordering of construction of `app` is still challenging. - The constructing code of this object still needs to know how to construct each dependency of the object. - The constructing code of this object needs to explicitly import all the types. --- class: enlarge150 ### What is Type-based Dependency Injection? A dependency injection **container** keeps tracks of singletons or recipes for how to construct each type. By default when it goes to construct an object, it can just ask the container for each dependency based on the type signature of the class being constructed. If an object declares it consumes a dependency of type `X` (e.g. `HDAManager`), just query the container recursively for an object of type `X`. --- ### What happens to object construction? Once all the dependencies have been type annotated properly and the needed singletons have been configured. ```python dcm = DatasetCollectionManager( self.model, self.security, HDAManager(self), HistoryManager(self), GalaxyTagHandler(self.model.context), LDDAManager(self) ) ``` becomes ```python dcm = container[DatasetCollectionManager] ``` --- class: enlarge150 ### Picking a Library Many of the existing DI libraries for Python predate widespread Python 3 and don't readily infer things based on types. The benefits of typing and DI are both enhanced by the other - so it was important to pick one that could do type-based injection. We went with Lagom, but we've built abstractions that would make it very easy to switch. --- ### Lagom ![Lagom Website](../../images/lagom_ss.png) https://lagom-di.readthedocs.io/en/latest/ --- ### DI and Controllers - FastAPI FastAPI controllers allowed some basic dependency injection. ```python def get_tags_manager() -> TagsManager: return TagsManager() @cbv(router) class FastAPITags: manager: TagsManager = Depends(get_tags_manager) ... ``` Dependency injection allows for type checking but doesn't use type inference (requires factory functions, etc..) https://fastapi.tiangolo.com/tutorial/dependencies/ --- ### DI and Controllers - FastAPI Limitations Also we have two different controller styles and only the new FastAPI allowed dependency injection. ```python def get_tags_manager() -> TagsManager: return TagsManager() @cbv(router) class FastAPITags: manager: TagsManager = Depends(get_tags_manager) ... class TagsController(BaseAPIController): def __init__(self, app): super().__init__(app) self.manager = TagsManager() ``` --- class: reduce90 ### DI and Controllers - Unified Approach ```diff -def get_tags_manager() -> TagsManager: - return TagsManager() - - @cbv(router) class FastAPITags: - manager: TagsManager = Depends(get_tags_manager) + manager: TagsManager = depends(TagsManager) @router.put( '/api/tags', @@ -58,11 +54,8 @@ def update( self.manager.update(trans, payload) -class TagsController(BaseAPIController): - - def __init__(self, app): - super().__init__(app) - self.manager = TagsManager() +class TagsController(BaseGalaxyAPIController): + manager: TagsManager = depends(TagsManager) ``` Building dependency injection into our application and not relying on FastAPI allows for dependency injection that is *less verbose*, available uniformly across the application, *works for the legacy controllers identically*. --- ### DI and Tasks - Framework From `lib/galaxy/celery/tasks.py` ```python from lagom import magic_bind_to_container ... def galaxy_task(func): CELERY_TASKS.append(func.__name__) app = get_galaxy_app() if app: return magic_bind_to_container(app)(func) return func ``` `magic_bind_to_container` to binds function parameters to a specified Lagom DI container automatically. --- ### DI and Tasks - Examples From `lib/galaxy/celery/tasks.py` ```python @celery_app.task(ignore_result=True) @galaxy_task def purge_hda(hda_manager: HDAManager, hda_id): hda = hda_manager.by_id(hda_id) hda_manager._purge(hda) @celery_app.task @galaxy_task def set_metadata(hda_manager: HDAManager, ldda_manager: LDDAManager, dataset_id, model_class='HistoryDatasetAssociation'): if model_class == 'HistoryDatasetAssociation': dataset = hda_manager.by_id(dataset_id) elif model_class == 'LibraryDatasetDatasetAssociation': dataset = ldda_manager.by_id(dataset_id) dataset.datatype.set_meta(dataset) ``` --- ![Decomposed App](../../images/app_decomposed.plantuml.svg) --- ### Tips for Designing New Galaxy Backend Components - Consume only the related components you need to avoid `app` when possible. - Annotate inputs to the component with Python types. - Use interface types to shield consumers from implementation details. - Rely on Galaxy's dependency injection to construct the component and provide it to consumers. --- ## Galaxy Tasks *The architecture surrounding Galaxy task management.* --- ![Processing requests on the server](../../images/asgi_app.plantuml.svg) ??? Web servers are a terrible place to do work. Traditional Python WSGI servers are meant for processing requests that take less a minute - they are meant for long running tasks. This request/response cycle is inappropriate for deleting all the files in a history, submitted 10,000 batch jobs for a collection, building a zip file for a library folder. --- ![Zoom in on Backend](../../images/core_backend_controllers.plantuml.svg) --- ![Infrastructure including Celery](../../images/core_backend_celery.plantuml.svg) ??? Handling a task description off to Celery allows the web server to respond right away and avoid various hacks. Celery is meant for these long running tasks and has a set of operations for handling them properly. --- ![Celery Overview](https://d33wubrfki0l68.cloudfront.net/f6a5a0c33eac1250034747d375da9a396e5488ce/0196f/media/async-task-python.png) --- class: enlarge150 ### Downsides of Celery Adds more complexity to deploying Galaxy. Celery needs to be available to Galaxy at runtime, production Galaxy instances need a broker and a backend. --- class: reduce90 ### Gravity + Celery .code[``` $ galaxy Registered galaxy config: /home/nate/work/galaxy/config/galaxy.yml Creating or updating service gunicorn Creating or updating service celery Creating or updating service celery-beat celery: added process group 2022-01-20 14:44:24,619 INFO spawned: 'celery' with pid 291651 celery-beat: added process group 2022-01-20 14:44:24,620 INFO spawned: 'celery-beat' with pid 291652 gunicorn: added process group 2022-01-20 14:44:24,622 INFO spawned: 'gunicorn' with pid 291653 celery STARTING celery-beat STARTING gunicorn STARTING ==> /home/nate/work/galaxy/database/gravity/log/gunicorn.log <== ...log output follows... ```] ??? Start Galaxy with Gravity starts not only the Python web server (gunicorn) running the Galaxy application but also celery and required services. --- ![Celery tasks being registered at startup](../../images/celery_tasks_list.png) --- class: enlarge150 ### Declaring a Task - Placed in `galaxy.celery.tasks`. - We've placed a layer around Celery to mirror what we're with API endpoints. - Typed functions with Pydantic inputs implicitly mapped. - Implicit type based dependency injection from Galaxy's DI container (using Lagom) - Feels a lot like writing an API endpoint. --- class: enlarge150 ### A Simple Task .code[``` @galaxy_task( ignore_result=True, action="setting up export history job" ) def export_history( model_store_manager: ModelStoreManager, request: SetupHistoryExportJob, ): model_store_manager.setup_history_export_job(request) ```] --- class: enlarge150 ### The `galaxy_task` Decorator .code[``` @galaxy_task( ignore_result=True, action="setting up export history job" ) def export_history( model_store_manager: ModelStoreManager, request: SetupHistoryExportJob, ): model_store_manager.setup_history_export_job(request) ```] - `galaxy_task` is a wrapper around Celery's `task` decorator - Wrap a simple function to turn it into a task. - Ensure all inputs are JSON serializable or components in Galaxy's dependency injection container --- class: enlarge150 ### Celery and Pydantic The `request` argument to `export_history` is a Pydantic model type named `SetupHistoryExportJob`. These are mostly defined in `galaxy.schema.tasks`. .code[``` from pydantic import BaseModel class SetupHistoryExportJob(BaseModel): history_id: int job_id: int store_directory: str include_files: bool include_hidden: bool include_deleted: bool ```] --- class: enlarge200 ### Celery and Pydantic - Implementation - Custom JSON encoding and decoding to adapt Celery to Pydantic. - Implemented in `galaxy.celery._serialization`. - Inject `__type__` and `__class__` attributes into JSON description. - `@galaxy_task` decorator sets Celery `serializer` attribute. --- class: enlarge150 ### Celery and Dependency Injection .code[``` @galaxy_task( ignore_result=True, action="setting up export history job" ) def export_history( model_store_manager: ModelStoreManager, request: SetupHistoryExportJob, ): model_store_manager.setup_history_export_job(request) ```] - The type declaration on `model_store_manager` of `ModelStoreManager` causes the Galaxy manager object of this class to be passed to the function when the task is running. - Client does not need to have any knowledge of this class. --- ### Executing Tasks from Galaxy See `lib/galaxy/tools/imp_exp/__init__.py`: .code[``` from galaxy.schema.tasks import SetupHistoryExportJob ... request = SetupHistoryExportJob( history_id=history.id, job_id=self.job_id, store_directory=store_directory, include_files=True, include_hidden=include_hidden, include_deleted=include_deleted, ) export_history.delay(request=request) ```] The delay method is created implicitly from the `galaxy_task` decorator. --- class: enlarge200 ### Best Practices - Place tasks in `galaxy.celery.tasks`. - Keep the tasks as thin as possible (ideally simply delegate inputs to a manager or another Galaxy component independent of Celery). - Ensure required/injected Galaxy components as small and decomposed as possible. - Place new request definition argument types in `galaxy.schema.tasks`. --- ### Existing Tasks Success Stories --- class: enlarge150 ### PDF Export Problems - We added PDF export of Galaxy Markdown using weasyprint - Generation of PDF took too long, feature was quite unstable --- class: enlarge150 ### Short Term Storage (STS) - A Galaxy component for managing user downloadable files that only need to exist for a little time. - Traditionally, these kind of files have required a lot of hacking to do well in Galaxy (tracking transient request-like stuff in data model, etc..) - Not just unoptimized by default, but unusable - Required customizing nginx routes, special web server plugins, etc... https://github.com/galaxyproject/galaxy/pull/13691 --- class: enlarge150 .code[``` class GeneratePdfDownload(BaseModel): short_term_storage_request_id: str basic_markdown: str document_type: PdfDocumentType ```] --- class: enlarge120 ### Robust PDF Export .code[``` from galaxy.managers.markdown_util import generate_branded_pdf @galaxy_task( action="preparing Galaxy Markdown PDF for download" ) def prepare_pdf_download( request: GeneratePdfDownload, config: GalaxyAppConfiguration, short_term_storage_monitor: ShortTermStorageMonitor, ): generate_branded_pdf( request, config, short_term_storage_monitor, ) ```] --- class: enlarge120 ### Exporting Histories, Invocations, Libraries .code[``` @galaxy_task( action="generate and stage a workflow invocation store for download" ) def prepare_invocation_download( model_store_manager: ModelStoreManager, request: GenerateInvocationDownload, ): model_store_manager.prepare_invocation_download( request ) ```] https://github.com/galaxyproject/galaxy/pull/12533 --- class: enlarge150 ### Optimized Uploads - Decomposed job handling, precursor to migrating more job components to Celery - Converting uploads to tasks signficantly sped up running Galaxy tests - API tests went from 2.5 hours to 50 minutes - Amazing speed up for small jobs - Exploring task composition https://github.com/galaxyproject/galaxy/pull/13655 --- ### Uploads - Task Composition See `lib/galaxy/tools/execute.py` .code[``` async_result = ( setup_fetch_data.s(job_id, raw_tool_source=raw_tool_source) | fetch_data.s(job_id=job_id).set(queue="galaxy.external") | set_job_metadata.s( extended_metadata_collection="extended" in tool.app.config.metadata_strategy, job_id=job_id, ).set( queue="galaxy.external", link_error=finish_job.si(job_id=job_id, raw_tool_source=raw_tool_source) ) | finish_job.si(job_id=job_id, raw_tool_source=raw_tool_source) )() ```] --- class: enlarge200 ### Batch Operations Task-based operations enable the most expensive of the new history's batch operations. - Changing datatypes - Purging datasets https://github.com/galaxyproject/galaxy/pull/14042 --- class: enlarge200 ### Future Work - *Migrating tool submission to tasks* - Workflow scheduling - Importing shared histories https://github.com/galaxyproject/galaxy/issues/11721 --- ## Application Components - Models, Managers, and Services *The architecture surrounding Galaxy components.* --- ![This section will talk about that manager layer and what lies below](../../images/asgi_app.plantuml.svg) --- There are many ways to describe and visualize the Galaxy server architecture, one is to imagine the Galaxy database as the ultimate source for Galaxy "stuff" and the API controllers as the ultimate sink. In this architecture imagining of Galaxy, managers are the layer meant to mediate all controller interactions (and isolate the backend from the web framework) while the model layer is meant to mediate all database interactions (and isolate the backend from database internals). --- ![Models and Managers](../../images/core_models_managers.plantuml.svg) --- class: enlarge150 ### Services Handle API and web processing details of requests and responses at a high-level. Thin layer below the controllers to shield applciation logic from FastAPI internals. In practice, it is totally fine to skip this layer and have FastAPI controllers talk directly to managers. --- class: enlarge150 ### Managers High-level business logic that ties all of these components together. Controllers should ideally be thin wrappers around actions defined in managers. Whenever a model requires more than just the database, the operation should be defined in a manager instead of in the model. --- ### Managers - Some Key Files ![Key Managers](../../images/core_files_managers.plantuml.svg) --- ### Managers - Some Helpers ![Manager Helpers](../../images/core_files_managers_helpers.plantuml.svg) --- ### Galaxy Models - Database interactions powered by SQLAlchemy - https://www.sqlalchemy.org/. - Galaxy doesn't think in terms of "rows" but "objects". - Classes for Galaxy model objects defined in `lib/galaxy/model/__init__.py`. - Classes mapped to database objects in same module via "declarative mapping". - Classes/attributes mapped to tables/columns - Associations between classes mapped to relationships between tables --- ![SQLAlchemy Architecture](../../images/sqla_arch_small.png) --- ### Galaxy Database Schema Migrations - Automated execution of incremental, reversible changes to the database schema. - Performed to update or revert the database schema to a newer or older version. - Powered by Alembic - https://alembic.sqlalchemy.org/. - (as of 22.05; prior to that by SQLAlchemy Migrate) - Each file in `lib/galaxy/model/migrations/alembic/versions_gxy` represents a migration description - `e7b6dcb09efd_create_gxy_branch.py` - `6a67bf27e6a6_deferred_data_tables.py` - `b182f655505f_add_workflow_source_metadata_column.py` --- ### More on Schema Migrations - Great documentation in code README - `lib/galaxy/model/migrations/README.md` - Admin perspective on how to migrate databases forward and revert on problems. - Developer persepctive on how to add new revisions. - Galaxy's data model is split into the galaxy model and the legacy install model: - Persisted in one combined database or two separate databases - Represented by 2 migration branches: "gxy" and "tsi" - Schema changes defined in revision modules: - `lib/galaxy/model/migrations/alembic/versions_gxy` (gxy branch: galaxy model) - `lib/galaxy/model/migrations/alembic/versions_tsi` (tsi branch: legacy install model) --- ![Galaxy Schema](../../images/galaxy_schema.png) ### Database Diagram https://galaxyproject.org/admin/internals/data-model/ --- ![HDA](../../images/hda.svg) --- ![HDA Dataset](../../images/hda_dataset.plantuml.svg) --- ### Dataset Metadata - Typed key-value pairs attached to HDA. - Keys and types defined at the datatype level. - Can be used by tools to dynamically control the tool form. ??? --- ![HDAs and HDCAs](../../images/hda_hdca.plantuml.svg) --- ![Workflows](../../images/workflow_definition.svg) --- ![Workflow Running](../../images/workflow_run.svg) --- ![Libraries](../../images/libraries.svg) --- ![Library Permissions](../../images/library_permissions.svg) --- ## Application Components - Plugins *The architecture of pluggable Galaxy components.* --- ![Models and Managers](../../images/core_models_managers.plantuml.svg) --- ### Plugins All the Way Down ![Plugins](../../images/core_plugins_overview.plantuml.svg) --- #### Datatypes ![Datatype Files](../../images/core_files_datatypes.plantuml.svg) Developer docs on adding new datatypes can be found at https://docs.galaxyproject.org/en/latest/dev/data_types.html. --- #### Tools ![ToolBox Classes](../../images/core_toolbox_classes.plantuml.svg) Three major classes can be summarized as - the `ToolBox` contains `Tool` objects that execute a `ToolAction`. --- #### Subclasses of Tool ![Tool Classes](../../images/core_tool_classes.plantuml.svg) --- ![Running Tools](../../images/core_tool_sequence.plantuml.svg) --- ### A Little About Jobs - Job is placed into the database and picked up by the job handler. - Job handler (`JobHandler`) watches the job and transitions job's state - common startup and finishing. - Job mapper (`JobRunnerMapper`) decides the "destination" for a job. - Job runner (e.g. `DrammaJobRunner`) actual runs the job and provides an interface for checking status. --- ### Job Runners ![Job Runners](../../images/core_runner_classes.plantuml.svg) --- ![Handling Jobs](../../images/core_jobs_sequence.plantuml.svg) --- ![Data Managers](../../images/data_managers.svg) --- ### Visualization Plugins Adding new visualizations to a Galaxy instance - Configuration file (XML) - Base template (Mako or JavaScript) - Additional static data if needed (CSS, JS, …) .footnote[[Learn more about it with our visualization tutorial.](/training-material/topics/dev/tutorials/visualization-generic/slides.html)] --- class: reduce70 ```xml <?xml version="1.0" encoding="UTF-8"?> <!DOCTYPE visualization SYSTEM "../../visualization.dtd"> <visualization name="ChiRAViz"> <description>ChiRAViz</description> <data_sources> <data_source> <model_class>HistoryDatasetAssociation</model_class> <test type="isinstance" test_attr="datatype" result_type="datatype">binary.ChiraSQLite</test> <to_param param_attr="id">dataset_id</to_param> </data_source> </data_sources> <params> <param type="dataset" var_name_in_template="hda" required="true">dataset_id</param> </params> <template>chiraviz.mako</template> </visualization> ``` --- template: left-aligned ### Visualization Examples All in `config/plugins/visualizations`: - `chiraviz` - Latest addition mid-2020, demonstrates current state of the art building and packing. [#9562](https://github.com/galaxyproject/galaxy/pull/9562) - `csg` - Chemical structure viewer - `graphviz` - Visualize graph data using [cytoscape.js](http://www.cytoscape.org/) - `charts` - Classic charts as well as some integrated BioJS visualizations - `trackster` - Genome browser, deeply tied to Galaxy internals. --- ### Data Providers Provide efficient access to data for viz & API Framework provides direct link to read the raw dataset or use data providers to adapt it In config, assert that visualization requires a given type of data providers Data providers process data before sending to browser - slice, filter, reformat, ... --- ### Object Store .strike[```python >>> fh = open(dataset.file_path, 'w') >>> fh.write(‘foo’) >>> fh.close() >>> fh = open(dataset.file_path, ‘r’) >>> fh.read() ```] ```python >>> app.objectstore.update_from_file(dataset, file_name=‘foo.txt’) >>> app.objectstore.get_data(dataset) >>> app.objectstore.get_data(dataset, start=42, count=4096) ``` --- ![Object Store](../../images/objectstore.plantuml.svg) These implementation are found below `lib/galaxy/objectstore/`. --- ![File Source Plugins](../../images/core_file_sources.plantuml.svg) --- # FileSources vs ObjectStores ObjectStores provide datasets not files, the files are organized logically in a very flat way around a dataset. FilesSources instead provide files and directories, not datasets. A FilesSource is meant to be browsed in hierarchical fashion - and also has no concept of extra files, etc.. The former is assumed to be persistent, the latter makes no such assumption. --- More information about File source plugins can be found at http://bit.ly/gcc21files --- #### Workflow Modules ![Workflow Modules](../../images/core_workflow_modules.plantuml.svg) All these modules are found in `lib/galaxy/workflow/modules.py`. --- #### `lib/galaxy/util/plugin_config.py` Standardized way to load both a set of possible plugin class implementations from a directory of Python files and to parse either an XML or YAML/JSON description of configured plugins. --- #### `lib/galaxy/util/plugin_config.py` Example Files ![Workflow Modules](../../images/core_files_plugin_example.plantuml.svg) --- #### `lib/galaxy/util/plugin_config.py` Plugin Implementations ```python def plugins_dict(module, plugin_type_identifier): plugin_dict = {} for plugin_module in import_submodules(module, ordered=True): for clazz in __plugin_classes_in_module(plugin_module): plugin_type = getattr(clazz, plugin_type_identifier, None) if plugin_type: plugin_dict[plugin_type] = clazz return plugin_dict ``` --- #### Pieces of `lib/galaxy/tool_util/deps/containers.py` ```python class ContainerRegistry(object): def __init__(self, app_info, mulled_resolution_cache=None): self.resolver_classes = self.__resolvers_dict() self.app_info = app_info self.container_resolvers = self.__build_container_resolvers(app_info) # ... other stuff here def __build_container_resolvers(self, app_info): conf_file = getattr(app_info, 'containers_resolvers_config_file', None) plugin_source = plugin_config.plugin_source_from_path(conf_file) return self._parse_resolver_conf(plugin_source) def _parse_resolver_conf(self, plugin_source): extra_kwds = { 'app_info': self.app_info } return plugin_config.load_plugins( self.resolver_classes, plugin_source, extra_kwds ) def __resolvers_dict(self): import galaxy.tool_util.deps.container_resolvers return plugin_config.plugins_dict( galaxy.tool_util.deps.container_resolvers, 'resolver_type' ) ``` --- #### Pieces of `lib/galaxy/tool_util/deps/container_resolvers/mulled.py` ```python class CachedMulledDockerContainerResolver(ContainerResolver): resolver_type = "cached_mulled" def __init__(self, app_info=None, namespace="biocontainers", hash_func="v2", **kwds): super(CachedMulledDockerContainerResolver, self).__init__(app_info) self.namespace = namespace self.hash_func = hash_func def resolve(self, enabled_container_types, tool_info, **kwds): # ... do the magic with configured plugin ``` --- `container_resolvers_conf.xml` ```xml <container_resolvers> <cached_mulled /> <cached_mulled namespace="mycustom" /> </container_resolvers> ``` `container_resolvers_conf.yml` ```yaml - resolver_type: cached_mulled - resolver_type: cached_mulled namespace: mycustom ``` --- ## Client Architecture *The architecture of Galaxy's web user interface.* --- template: left-aligned ### Client Directories - Source JavaScript for the client is in `client/src`. - Source stylesheets are in `client/src/style`. - "Packed" bundles served by Galaxy stored in `static/dist` - `run.sh` uses `git diff` to try to determine if client needs to be built before starting Galaxy - webpack builds these "compiled" artifacts Upshot - to develop against the client, modify files in `client/` and rebuild with `make client` before deployment. --- class: normal ### Building the Client - Makefile Targets ```Makefile client: node-deps ## Rebuild all client-side artifacts (for local dev) cd client && yarn run build client-production-maps: node-deps ## Build optimized artifacts with sourcemaps. cd client && yarn run build-production-maps client-watch: node-deps ## Rebuild client on each change. cd client && yarn run watch client-format: node-deps ## Reformat client code cd client && yarn run prettier client-lint: client-eslint client-format-check ## ES lint and check format of client client-test: node-deps ## Run JS unit tests cd client && yarn run test client-test-watch: client ## Watch and run all client unit tests on changes cd client && yarn run jest-watch node-deps: ## Install NodeJS and dependencies. ``` --- ### Automatically Reloading During Development The following command rebuilds the application on each change. ``` make client-watch ``` This is still a relatively slow process, an extra client development server can be started that proxies non-client requests to your Galaxy server and selectively reloads only what is needed during active development (hot module replacement or HMR). ``` make client-dev-server ``` Make sure to open Galaxy at http://localhost:8081 instead to point at the client proxy. --- class: white ![What is Webpack](../../images/what-is-webpack.svg) --- class: enlarge150 ### webpack in Galaxy Packs and "transpiles" Galaxy ES6 code (.js), Galaxy Vue modules (.vue), libraries from npm, scss stylesheets (.scss) into browser native bundles. Hundreds of high-level well organized files into optimized single files that can be quickly downloaded. Lots of active development and complexity around Viz plugins and dependencies for instance, but the webpack configuration file in `config/webpack.config.js` is fairly straightforward. --- class: white ![Webpack in Action](../../images/jsload.png) --- ### Stylesheets - Galaxy shared stylesheets are generally defined using the SCSS syntax - SCSS is a high-level superset of CSS - https://sass-lang.com/documentation/syntax - `sass` is leveraged by webpack to convert these styles to native CSS at client build time - Rebuild style with `make style` - Galaxy's SCSS files can be found in `client/src/style/scss/` --- ### Package and Build Files ![Client Build Files](../../images/core_files_client_build.plantuml.svg) --- ### Source Files ![Client Build Files](../../images/core_files_client_sources.plantuml.svg) --- ### ES6 The client is built from JavaScript source files. We use ES6 JavaScript. A tutorial to help learn JavaScript generally might be https://www.w3schools.com/js/. For someone familiar with JavaScript but that wants a primer on the new language features in ES6, https://www.w3schools.com/js/js_es6.asp may be more appropriate. --- ### Vue Vue.js is a reactive framework for building web client applications. We chose Vue.js over React initially because of its focus on allowing developers to incrementally or progressively replace pieces of complex existing applications. The idea behind Vue.js is fairly simple to pick up and there is a lot of great tutorials and videos available. https://vuejs.org/v2/guide/ is a really good jumping off point. --- ### Vuex > Vuex is a state management pattern + library for Vue.js applications. It serves as a centralized store for all the components in an application, with rules ensuring that the state can only be mutated in a predictable fashion. https://vuex.vuejs.org/ --- ### Client Unit Tests https://jestjs.io/ Configured in `client/src/jest/jest.config.js`. Vue tests are placed beside components in `client/src`, more tests in `client/test/qunit/tests` and `client/test/jest/standalone/`. --- ### Vue Test Utils > Vue Test Utils is the official unit testing utility library for Vue.js. https://vue-test-utils.vuejs.org/ Really nice reference library documentation. A lot of helpers and concepts to unit test Vue components. --- ### Client Unit Test Design Tips https://github.com/galaxyproject/galaxy/tree/dev/client/docs/src/component-design/unit-testing - Clearly document the intent of your test - Implement logic in pure functions when possible - Wrap native browser resources in a function so they can be easily mocked --- ### Webhooks in Galaxy Webhooks is a system in Galaxy which can be used to write small JS and/or Python functions to change predefined locations in the Galaxy client. <br><br> In short: A plugin infrastructure for the Galaxy UI .footnote[You can learn more about webhooks using our webhook [training](/training-material/topics/dev/tutorials/webhooks/slides.html).] --- ### Webhook masthead example ![A person shaped icon in the Galaxy masthead is being hovered over and the popup reads "Show Username", presumably a custom webhook from a tutorial.](../../images/webhook_masthead.png) At the header menu: Enabling the overlay search, link to communities ... .footnote[You can learn more about webhooks using our webhook [training](/training-material/topics/dev/tutorials/webhooks/slides.html).] --- ### Webhook tool/workflow example ![Screenshot of Galaxy with the job completion screen shown and a PhD comic image shown below.](../../images/webhook_tool.png) Shown after tool or workflow execution. Comics, citations, support ... .footnote[You can learn more about webhooks using our webhook [training](/training-material/topics/dev/tutorials/webhooks/slides.html).] --- ### Webhook history-menu example ![A section of the history menu is labelled Webhooks and shows a custom menu entry.](../../images/webhook_history.png) Adds an entry to the history menu - no functionality as of now .footnote[You can learn more about webhooks using our webhook [training](/training-material/topics/dev/tutorials/webhooks/slides.html).] --- ## Dependencies --- template: left-aligned ### Dependencies - Python `script/common_startup.sh` sets up a `virtualenv` with required dependencies in `$GALAXY_ROOT/.venv` (or `$GALAXY_VIRTUAL_ENV` if set). - Check for existing virtual environment, if it doesn't exist check for `virtualenv`. - If `virtualenv` exists, use it. Otherwise download it as a script and setup a virtual environment using it. - `. "$GALAXY_VIRTUAL_ENV/bin/activate"` - Upgrade to latest `pip` to allow use of binary wheels. - `pip install -r requirements.txt --index-url https://wheels.galaxyproject.org/simple` - Install dozens of dependencies. --- template: left-aligned ### Dependencies - JavaScript - Dependencies are defined in `client/package.json`. - These are fetched from npm and compiled into bundles as part of `make client` and related `Makefile` targets. --- ## Galaxy Startup Process --- ### Cloning Galaxy ```bash $ git clone https://github.com/galaxyproject/galaxy.git galaxy Cloning into 'galaxy'... remote: Counting objects: 173809, done. remote: Total 173809 (delta 0), reused 0 (delta 0), pack-reused 173809 Receiving objects: 100% (173809/173809), 55.18 MiB | 11.08 MiB/s, done. Resolving deltas: 100% (137885/137885), done. Checking connectivity... done. $ cd galaxy $ git checkout -b master origin/master Branch master set up to track remote branch master from origin. Switched to a new branch 'master' $ sh run.sh ``` --- class: reduce90 ### Copying Configs ```bash $ sh run.sh Initializing config/migrated_tools_conf.xml from migrated_tools_conf.xml.sample Initializing config/shed_tool_conf.xml from shed_tool_conf.xml.sample Initializing config/shed_tool_data_table_conf.xml from shed_tool_data_table_conf.xml.sample Initializing config/shed_data_manager_conf.xml from shed_data_manager_conf.xml.sample Initializing tool-data/shared/ucsc/builds.txt from builds.txt.sample Initializing tool-data/shared/ucsc/manual_builds.txt from manual_builds.txt.sample Initializing tool-data/shared/ucsc/ucsc_build_sites.txt from ucsc_build_sites.txt.sample Initializing tool-data/shared/igv/igv_build_sites.txt from igv_build_sites.txt.sample Initializing tool-data/shared/rviewer/rviewer_build_sites.txt from rviewer_build_sites.txt.sample Initializing static/welcome.html from welcome.html.sample ``` --- ### Setting up `.venv` and `pip` ``` Using real prefix '/usr' New python executable in .venv/bin/python Installing setuptools, pip, wheel...done. Activating virtualenv at .venv Collecting pip>=8.1 Using cached pip-8.1.2-py2.py3-none-any.whl Installing collected packages: pip Found existing installation: pip 7.1.2 Uninstalling pip-7.1.2: Successfully uninstalled pip-7.1.2 Successfully installed pip-8.1.2 ``` --- class: reduce70 ### Installing Dependencies .code[``` Collecting bx-python==0.7.3 (from -r requirements.txt (line 2)) Downloading https://wheels.galaxyproject.org/packages/bx_python-0.7.3-cp27-cp27mu-manylinux1_x86_64.whl (2.1MB) Collecting MarkupSafe==0.23 (from -r requirements.txt (line 3)) Downloading https://wheels.galaxyproject.org/packages/MarkupSafe-0.23-cp27-cp27mu-manylinux1_x86_64.whl Collecting PyYAML==3.11 (from -r requirements.txt (line 4)) Downloading https://wheels.galaxyproject.org/packages/PyYAML-3.11-cp27-cp27mu-manylinux1_x86_64.whl (367kB) Collecting SQLAlchemy==1.0.8 (from -r requirements.txt (line 5)) Downloading https://wheels.galaxyproject.org/packages/SQLAlchemy-1.0.8-cp27-cp27mu-manylinux1_x86_64.whl (1.0MB) Collecting mercurial==3.7.3 (from -r requirements.txt (line 6)) Downloading https://wheels.galaxyproject.org/packages/mercurial-3.7.3-cp27-cp27mu-manylinux1_x86_64.whl (1.5MB) ... ... Building wheels for collected packages: repoze.lru Running setup.py bdist_wheel for repoze.lru: started Running setup.py bdist_wheel for repoze.lru: finished with status 'done' Stored in directory: /home/john/.cache/pip/wheels/b2/cd/b3/7e24400bff83325a01d492940eff6e9579f553f33348323d79 Successfully built repoze.lru Installing collected packages: bx-python, MarkupSafe, PyYAML, SQLAlchemy, mercurial, numpy, pycrypto, six, Paste, PasteDeploy, docutils, wchartype, repoze.lru, Routes, WebOb, WebHelpers, Mako, pytz, Babel, Beaker, dictobj, nose, Parsley, Whoosh, Markdown, Cheetah, requests, boto, requests-toolbelt, bioblend, anyjson, amqp, kombu, psutil, PasteScript, pulsar-galaxy-lib, sqlparse, pbr, decorator, Tempita, sqlalchemy-migrate, pyparsing, svgwrite, ecdsa, paramiko, Fabric, pysam Successfully installed Babel-2.0 Beaker-1.7.0 Cheetah-2.4.4 Fabric-1.10.2 Mako-1.0.2 Markdown-2.6.3 MarkupSafe-0.23 Parsley-1.3 Paste-2.0.2 PasteDeploy-1.5.2 PasteScript-2.0.2 PyYAML-3.11 Routes-2.2 SQLAlchemy-1.0.8 Tempita-0.5.3.dev0 WebHelpers-1.3 WebOb-1.4.1 Whoosh-2.7.4 amqp-1.4.8 anyjson-0.3.3 bioblend-0.7.0 boto-2.38.0 bx-python-0.7.3 decorator-4.0.2 dictobj-0.3.1 docutils-0.12 ecdsa-0.13 kombu-3.0.30 mercurial-3.7.3 nose-1.3.7 numpy-1.9.2 paramiko-1.15.2 pbr-1.8.0 psutil-4.1.0 pulsar-galaxy-lib-0.7.0.dev4 pycrypto-2.6.1 pyparsing-2.1.1 pysam-0.8.4+gx1 pytz-2015.4 repoze.lru-0.6 requests-2.8.1 requests-toolbelt-0.4.0 six-1.9.0 sqlalchemy-migrate-0.10.0 sqlparse-0.1.16 svgwrite-1.1.6 wchartype-0.1 ```] --- class: reduce70 ### Initial Debugging as App Starts .code[``` Activating virtualenv at .venv DEBUG:galaxy.app:python path is: /home/john/workspace/galaxy-clean/scripts, /home/john/workspace/galaxy-clean/lib, /home/john/workspace/galaxy-clean/.venv/lib/python2.7,/home/john/workspace/galaxy-clean/.venv/lib/python2.7/plat-x86_64-linux-gnu, /home/john/workspace/galaxy-clean/.venv/lib/python2.7/lib-tk, /home/john/workspace/galaxy-clean/.venv/lib/python2.7/lib-old, /home/john/workspace/galaxy-clean/.venv/lib/python2.7/lib-dynload, /usr/lib/python2.7, /usr/lib/python2.7/plat-x86_64-linux-gnu, /usr/lib/python2.7/lib-tk, /home/john/workspace/galaxy-clean/.venv/local/lib/python2.7/site-packages INFO:galaxy.config:Logging at '10' level to 'stdout' galaxy.queue_worker INFO 2016-06-23 19:11:51,925 Initializing main Galaxy Queue Worker on sqlalchemy+sqlite:///./database/control.sqlite?isolation_level=IMMEDIATE tool_shed.tool_shed_registry DEBUG 2016-06-23 19:11:51,951 Loading references to tool sheds from ./config/tool_sheds_conf.xml.sample tool_shed.tool_shed_registry DEBUG 2016-06-23 19:11:51,951 Loaded reference to tool shed: Galaxy Main Tool Shed galaxy.app DEBUG 2016-06-23 19:11:51,956 Using "galaxy.yml" config file: /home/john/workspace/galaxy-clean/config/galaxy.yml.sample ```] --- class: reduce70 ### Database Migrations .code[``` migrate.versioning.repository DEBUG 2016-06-23 19:11:51,993 Loading repository lib/galaxy/model/migrate... migrate.versioning.script.base DEBUG 2016-06-23 19:11:51,994 Loading script lib/galaxy/model/migrate/versions/0001_initial_tables.py... migrate.versioning.script.base DEBUG 2016-06-23 19:11:51,994 Script lib/galaxy/model/migrate/versions/0001_initial_tables.py loaded successfully migrate.versioning.script.base DEBUG 2016-06-23 19:11:51,994 Loading script lib/galaxy/model/migrate/versions/0002_metadata_file_table.py... migrate.versioning.script.base DEBUG 2016-06-23 19:11:52,009 Loading script lib/galaxy/model/migrate/versions/0131_subworkflow_and_input_parameter_modules.py... ... galaxy.model.migrate.check INFO 2016-06-23 19:13:32,812 Migrating 128 -> 129... galaxy.model.migrate.check INFO 2016-06-23 19:13:33,436 galaxy.model.migrate.check INFO 2016-06-23 19:13:33,437 Migration script to allow invalidation of job external output metadata temp files galaxy.model.migrate.check INFO 2016-06-23 19:13:33,437 galaxy.model.migrate.check INFO 2016-06-23 19:13:33,437 galaxy.model.migrate.check INFO 2016-06-23 19:13:33,437 Migrating 129 -> 130... galaxy.model.migrate.check INFO 2016-06-23 19:13:34,325 galaxy.model.migrate.check INFO 2016-06-23 19:13:34,325 Migration script to change the value column of user_preference from varchar to text. galaxy.model.migrate.check INFO 2016-06-23 19:13:34,325 galaxy.model.migrate.check INFO 2016-06-23 19:13:34,325 galaxy.model.migrate.check INFO 2016-06-23 19:13:34,326 Migrating 130 -> 131... galaxy.model.migrate.check INFO 2016-06-23 19:13:35,633 galaxy.model.migrate.check INFO 2016-06-23 19:13:35,633 Migration script to support subworkflows and workflow request input parameters galaxy.model.migrate.check INFO 2016-06-23 19:13:35,633 galaxy.model.migrate.check INFO 2016-06-23 19:13:35,633 ```] --- Everything after here happens every time --- class: reduce70 .code[``` migrate.versioning.repository DEBUG 2016-06-23 19:13:35,635 Loading repository lib/tool_shed/galaxy_install/migrate... migrate.versioning.script.base DEBUG 2016-06-23 19:13:35,635 Loading script lib/tool_shed/galaxy_install/migrate/versions/0001_tools.py... migrate.versioning.script.base DEBUG 2016-06-23 19:13:35,636 Script lib/tool_shed/galaxy_install/migrate/versions/0001_tools.py loaded successfully migrate.versioning.script.base DEBUG 2016-06-23 19:13:35,636 Loading script lib/tool_shed/galaxy_install/migrate/versions/0002_tools.py... migrate.versioning.script.base DEBUG 2016-06-23 19:13:35,636 Script lib/tool_shed/galaxy_install/migrate/versions/0002_tools.py loaded successfully migrate.versioning.script.base DEBUG 2016-06-23 19:13:35,636 Loading script lib/tool_shed/galaxy_install/migrate/versions/0003_tools.py... migrate.versioning.script.base DEBUG 2016-06-23 19:13:35,636 Script lib/tool_shed/galaxy_install/migrate/versions/0003_tools.py loaded successfully migrate.versioning.script.base DEBUG 2016-06-23 19:13:35,636 Loading script lib/tool_shed/galaxy_install/migrate/versions/0004_tools.py... migrate.versioning.script.base DEBUG 2016-06-23 19:13:35,636 Script lib/tool_shed/galaxy_install/migrate/versions/0004_tools.py loaded successfully migrate.versioning.script.base DEBUG 2016-06-23 19:13:35,636 Loading script lib/tool_shed/galaxy_install/migrate/versions/0005_tools.py... migrate.versioning.script.base DEBUG 2016-06-23 19:13:35,636 Script lib/tool_shed/galaxy_install/migrate/versions/0005_tools.py loaded successfully ... migrate.versioning.script.base DEBUG 2016-06-23 19:13:35,637 Script lib/tool_shed/galaxy_install/migrate/versions/0012_tools.py loaded successfully migrate.versioning.repository DEBUG 2016-06-23 19:13:35,637 Repository lib/tool_shed/galaxy_install/migrate loaded successfully tool_shed.galaxy_install.migrate.check DEBUG 2016-06-23 19:13:35,660 The main Galaxy tool shed is not currently available, so skipped tool migration 1 until next server startup galaxy.config INFO 2016-06-23 19:13:35,679 Install database targetting Galaxy's database configuration. ```] --- class: reduce70 .code[``` galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,748 Loading datatypes from ./config/datatypes_conf.xml.sample galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,749 Retrieved datatype module galaxy.datatypes.binary:Ab1 from the datatype registry. galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,750 Retrieved datatype module galaxy.datatypes.assembly:Amos from the datatype registry. galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,751 Retrieved datatype module galaxy.datatypes.text:Arff from the datatype registry. galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,751 Retrieved datatype module galaxy.datatypes.data:GenericAsn1 from the datatype registry. ... galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,822 Retrieved datatype module galaxy.datatypes.mothur:SquareDistanceMatrix from the datatype registry. galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,822 Retrieved datatype module galaxy.datatypes.mothur:LowerTriangleDistanceMatrix from the datatype registry. galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,822 Retrieved datatype module galaxy.datatypes.mothur:RefTaxonomy from the datatype registry. galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,822 Retrieved datatype module galaxy.datatypes.mothur:RefTaxonomy from the datatype registry. galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,823 Retrieved datatype module galaxy.datatypes.mothur:RefTaxonomy from the datatype registry. galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,823 Retrieved datatype module galaxy.datatypes.mothur:ConsensusTaxonomy from the datatype registry. galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,823 Retrieved datatype module galaxy.datatypes.mothur:TaxonomySummary from the datatype registry. galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,823 Retrieved datatype module galaxy.datatypes.mothur:Frequency from the datatype registry. galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,823 Retrieved datatype module galaxy.datatypes.mothur:Quantile from the datatype registry. galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,823 Retrieved datatype module galaxy.datatypes.mothur:Quantile from the datatype registry. galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,823 Retrieved datatype module galaxy.datatypes.mothur:Quantile from the datatype registry. galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,823 Retrieved datatype module galaxy.datatypes.mothur:Quantile from the datatype registry. galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,824 Retrieved datatype module galaxy.datatypes.mothur:Axes from the datatype registry. galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,824 Retrieved datatype module galaxy.datatypes.mothur:SffFlow from the datatype registry. galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,824 Retrieved datatype module galaxy.datatypes.mothur:CountTable from the datatype registry. ```] --- class: reduce70 .code[``` galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,824 Loaded sniffer for datatype 'galaxy.datatypes.mothur:Sabund' galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,824 Loaded sniffer for datatype 'galaxy.datatypes.mothur:Otu' galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,824 Loaded sniffer for datatype 'galaxy.datatypes.mothur:GroupAbund' galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,824 Loaded sniffer for datatype 'galaxy.datatypes.mothur:SecondaryStructureMap' galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,824 Loaded sniffer for datatype 'galaxy.datatypes.mothur:LowerTriangleDistanceMatrix' galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,824 Loaded sniffer for datatype 'galaxy.datatypes.mothur:SquareDistanceMatrix' galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,825 Loaded sniffer for datatype 'galaxy.datatypes.mothur:PairwiseDistanceMatrix' galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,825 Loaded sniffer for datatype 'galaxy.datatypes.mothur:Oligos' galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,825 Loaded sniffer for datatype 'galaxy.datatypes.mothur:Quantile' galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,825 Loaded sniffer for datatype 'galaxy.datatypes.mothur:Frequency' galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,825 Loaded sniffer for datatype 'galaxy.datatypes.mothur:LaneMask' galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,825 Loaded sniffer for datatype 'galaxy.datatypes.mothur:RefTaxonomy' galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,825 Loaded sniffer for datatype 'galaxy.datatypes.mothur:Axes' galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,825 Loaded sniffer for datatype 'galaxy.datatypes.constructive_solid_geometry:PlyAscii' galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,825 Loaded sniffer for datatype 'galaxy.datatypes.constructive_solid_geometry:PlyBinary' galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,825 Loaded sniffer for datatype 'galaxy.datatypes.constructive_solid_geometry:VtkAscii' galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,825 Loaded sniffer for datatype 'galaxy.datatypes.constructive_solid_geometry:VtkBinary' galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,825 Loaded sniffer for datatype 'galaxy.datatypes.interval:ScIdx' galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,825 Loaded sniffer for datatype 'galaxy.datatypes.tabular:Vcf' galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,826 Loaded sniffer for datatype 'galaxy.datatypes.binary:TwoBit' galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,826 Loaded sniffer for datatype 'galaxy.datatypes.binary:GeminiSQLite' galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,826 Loaded sniffer for datatype 'galaxy.datatypes.binary:MzSQlite' ... galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,832 Loaded sniffer for datatype 'galaxy.datatypes.images:Psd' galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,832 Loaded sniffer for datatype 'galaxy.datatypes.images:Xbm' galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,832 Loaded sniffer for datatype 'galaxy.datatypes.images:Rgb' galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,832 Loaded sniffer for datatype 'galaxy.datatypes.images:Pbm' galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,832 Loaded sniffer for datatype 'galaxy.datatypes.images:Pgm' galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,832 Loaded sniffer for datatype 'galaxy.datatypes.images:Xpm' galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,833 Loaded sniffer for datatype 'galaxy.datatypes.images:Eps' galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,833 Loaded sniffer for datatype 'galaxy.datatypes.images:Rast' galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,833 Loaded sniffer for datatype 'galaxy.datatypes.binary:OxliCountGraph' galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,833 Loaded sniffer for datatype 'galaxy.datatypes.binary:OxliNodeGraph' galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,833 Loaded sniffer for datatype 'galaxy.datatypes.binary:OxliTagSet' galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,833 Loaded sniffer for datatype 'galaxy.datatypes.binary:OxliStopTags' galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,833 Loaded sniffer for datatype 'galaxy.datatypes.binary:OxliSubset' galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,833 Loaded sniffer for datatype 'galaxy.datatypes.binary:OxliGraphLabels' ``` ] --- class: reduce70 .code[``` galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,833 Loaded build site 'ucsc': tool-data/shared/ucsc/ucsc_build_sites.txt with display sites: main,test,archaea,ucla galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,834 Loaded build site 'gbrowse': tool-data/shared/gbrowse/gbrowse_build_sites.txt with display sites: modencode,sgd_yeast,tair,wormbase,wormbase_ws120,wormbase_ws140,wormbase_ws170,wormbase_ws180,wormbase_ws190,wormbase_ws200,wormbase_ws204,wormbase_ws210,wormbase_ws220,wormbase_ws225 galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,834 Loaded build site 'ensembl': tool-data/shared/ensembl/ensembl_sites.txt galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,834 Loaded build site 'ensembl_data_url': tool-data/shared/ensembl/ensembl_sites_data_URL.txt galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,834 Loaded build site 'igv': tool-data/shared/igv/igv_build_sites.txt galaxy.datatypes.registry DEBUG 2016-06-23 19:13:35,834 Loaded build site 'rviewer': tool-data/shared/rviewer/rviewer_build_sites.txt ```] --- class: reduce70 .code[``` galaxy.tools.data INFO 2016-06-23 19:13:35,871 Could not find tool data tool-data/all_fasta.loc, reading sample galaxy.tools.data DEBUG 2016-06-23 19:13:35,871 Loaded tool data table 'all_fasta' galaxy.tools.data INFO 2016-06-23 19:13:35,871 Could not find tool data tool-data/bfast_indexes.loc, reading sample galaxy.tools.data DEBUG 2016-06-23 19:13:35,871 Loaded tool data table 'bfast_indexes' galaxy.tools.data WARNING 2016-06-23 19:13:35,871 Cannot find index file 'tool-data/blastdb_p.loc' for tool data table 'blastdb_p' ... galaxy.tools.data DEBUG 2016-06-23 19:13:36,210 Loaded tool data table 'vcf_iobio' galaxy.tools.data INFO 2016-06-23 19:13:36,211 Could not find tool data tool-data/biom_simple_display.loc, reading sample galaxy.tools.data DEBUG 2016-06-23 19:13:36,211 Loaded tool data table 'biom_simple_display' ```] --- class: reduce70 ### Job Configuration, Citation Cache .code[``` galaxy.jobs DEBUG 2016-06-23 19:13:36,233 Loading job configuration from /home/john/workspace/galaxy-clean/config/galaxy.yml.sample galaxy.jobs DEBUG 2016-06-23 19:13:36,233 Done loading job configuration beaker.container DEBUG 2016-06-23 19:13:36,278 data file ./database/citations/data/container_file/4/48/48e563f148dc04d8b31c94878c138019862e580d.cache ```] --- class: reduce70 ### Load Toolbox .code[``` galaxy.tools.toolbox.base INFO 2016-06-23 19:13:36,279 Parsing the tool configuration ./config/tool_conf.xml.sample galaxy.tools.toolbox.base DEBUG 2016-06-23 19:13:36,291 Loaded tool id: upload1, version: 1.1.4 into tool panel.. galaxy.tools.toolbox.base DEBUG 2016-06-23 19:13:36,294 Loaded tool id: ucsc_table_direct1, version: 1.0.0 into tool panel.. galaxy.tools.toolbox.base DEBUG 2016-06-23 19:13:36,296 Loaded tool id: ucsc_table_direct_test1, version: 1.0.0 into tool panel.. galaxy.tools.toolbox.base DEBUG 2016-06-23 19:13:36,298 Loaded tool id: ucsc_table_direct_archaea1, version: 1.0.0 into tool panel.. ... galaxy.tools.toolbox.base DEBUG 2016-06-23 19:13:36,496 Loaded tool id: vcf_to_maf_customtrack1, version: 1.0.0 into tool panel.. galaxy.tools.toolbox.base INFO 2016-06-23 19:13:36,497 Parsing the tool configuration ./config/shed_tool_conf.xml galaxy.tools.toolbox.base INFO 2016-06-23 19:13:36,497 Parsing the tool configuration ./config/migrated_tools_conf.xml ```] --- class: reduce90 ### Tool Dependency Resolution and Indexing .code[``` galaxy.tools.deps WARNING 2016-06-23 19:13:36,498 Path './database/dependencies' does not exist, ignoring galaxy.tools.deps WARNING 2016-06-23 19:13:36,498 Path './database/dependencies' is not directory, ignoring galaxy.tools.deps DEBUG 2016-06-23 19:13:36,503 Unable to find config file './dependency_resolvers_conf.xml' galaxy.tools.search DEBUG 2016-06-23 19:13:36,560 Starting to build toolbox index. galaxy.tools.search DEBUG 2016-06-23 19:13:37,789 Toolbox index finished. It took: 0:00:01.229406 ```] --- class: reduce70 ### Display Applications .code[``` galaxy.datatypes.registry DEBUG 2016-06-23 19:13:37,795 Loaded display application 'ucsc_bam' for datatype 'bam', inherit=False. galaxy.datatypes.registry DEBUG 2016-06-23 19:13:37,797 Loaded display application 'ensembl_bam' for datatype 'bam', inherit=False. galaxy.datatypes.registry DEBUG 2016-06-23 19:13:37,833 Loaded display application 'igv_bam' for datatype 'bam', inherit=False. galaxy.datatypes.registry DEBUG 2016-06-23 19:13:37,834 Loaded display application 'igb_bam' for datatype 'bam', inherit=False. ... galaxy.datatypes.registry DEBUG 2016-06-23 19:13:38,002 Loaded display application 'igv_vcf' for datatype 'vcf_bgzip', inherit=False. galaxy.datatypes.registry DEBUG 2016-06-23 19:13:38,003 Loaded display application 'biom_simple' for datatype 'biom1', inherit=False. galaxy.datatypes.registry DEBUG 2016-06-23 19:13:38,003 Adding inherited display application 'ensembl_gff' to datatype 'gtf' galaxy.datatypes.registry DEBUG 2016-06-23 19:13:38,004 Adding inherited display application 'igv_gff' to datatype 'gtf' ... galaxy.datatypes.registry DEBUG 2016-06-23 19:13:38,007 Adding inherited display application 'gbrowse_interval_as_bed' to datatype 'bed6' galaxy.datatypes.registry DEBUG 2016-06-23 19:13:38,007 Adding inherited display application 'rviewer_interval' to datatype 'bed6' galaxy.datatypes.registry DEBUG 2016-06-23 19:13:38,007 Adding inherited display application 'igv_interval_as_bed' to datatype 'bed6' ```] --- class: reduce70 ### Datatype Converters .code[``` galaxy.datatypes.registry DEBUG 2016-06-23 19:13:38,010 Loaded converter: CONVERTER_Bam_Bai_0 galaxy.datatypes.registry DEBUG 2016-06-23 19:13:38,011 Loaded converter: CONVERTER_bam_to_bigwig_0 galaxy.datatypes.registry DEBUG 2016-06-23 19:13:38,012 Loaded converter: CONVERTER_bed_to_gff_0 galaxy.datatypes.registry DEBUG 2016-06-23 19:13:38,012 Loaded converter: CONVERTER_bed_to_bgzip_0 galaxy.datatypes.registry DEBUG 2016-06-23 19:13:38,013 Loaded converter: CONVERTER_bed_to_tabix_0 ... galaxy.datatypes.registry DEBUG 2016-06-23 19:13:38,096 Loaded converter: CONVERTER_cml_to_inchi galaxy.datatypes.registry DEBUG 2016-06-23 19:13:38,097 Loaded converter: CONVERTER_cml_to_sdf galaxy.datatypes.registry DEBUG 2016-06-23 19:13:38,098 Loaded converter: CONVERTER_cml_to_mol2 galaxy.datatypes.registry DEBUG 2016-06-23 19:13:38,099 Loaded converter: CONVERTER_ref_to_seq_taxomony ```] --- class: reduce90 ### Special Tools .code[``` galaxy.datatypes.registry DEBUG 2016-06-23 19:13:38,101 Loaded external metadata tool: __SET_METADATA__ galaxy.tools.special_tools DEBUG 2016-06-23 19:13:38,107 Loaded history import tool: __IMPORT_HISTORY__ galaxy.tools.special_tools DEBUG 2016-06-23 19:13:38,108 Loaded history export tool: __EXPORT_HISTORY__ ```] --- class: reduce70 ### Visualization Plugins .code[``` galaxy.web.base.pluginframework INFO 2016-06-23 19:13:38,109 VisualizationsRegistry, loaded plugin: charts galaxy.visualization.plugins.config_parser INFO 2016-06-23 19:13:38,110 Visualizations plugin disabled: Circster. Skipping... galaxy.visualization.plugins.config_parser INFO 2016-06-23 19:13:38,111 template syntax is deprecated: use entry_point instead galaxy.web.base.pluginframework INFO 2016-06-23 19:13:38,111 VisualizationsRegistry, loaded plugin: csg galaxy.visualization.plugins.config_parser INFO 2016-06-23 19:13:38,111 template syntax is deprecated: use entry_point instead galaxy.web.base.pluginframework INFO 2016-06-23 19:13:38,112 VisualizationsRegistry, loaded plugin: graphviz galaxy.web.base.pluginframework INFO 2016-06-23 19:13:38,112 VisualizationsRegistry, loaded plugin: phyloviz galaxy.web.base.pluginframework INFO 2016-06-23 19:13:38,113 VisualizationsRegistry, loaded plugin: scatterplot galaxy.visualization.plugins.config_parser INFO 2016-06-23 19:13:38,113 Visualizations plugin disabled: Sweepster. Skipping... galaxy.web.base.pluginframework INFO 2016-06-23 19:13:38,114 VisualizationsRegistry, loaded plugin: trackster ```] --- ### Tours .code[``` galaxy.tours INFO 2016-06-23 19:13:38,125 Loaded tour 'core.scratchbook' galaxy.tours INFO 2016-06-23 19:13:38,158 Loaded tour 'core.galaxy_ui' galaxy.tours INFO 2016-06-23 19:13:38,183 Loaded tour 'core.history' ```] --- class: reduce90 ### Job Handler and Runners .code[``` galaxy.jobs.manager DEBUG 2016-06-23 19:13:38,196 Starting job handler galaxy.jobs INFO 2016-06-23 19:13:38,196 Handler 'main' will load all configured runner plugins galaxy.jobs.runners.state_handler_factory DEBUG 2016-06-23 19:13:38,198 Loaded 'failure' state handler from module galaxy.jobs.runners.state_handlers.resubmit galaxy.jobs.runners DEBUG 2016-06-23 19:13:38,198 Starting 5 LocalRunner workers galaxy.jobs DEBUG 2016-06-23 19:13:38,200 Loaded job runner 'galaxy.jobs.runners.local:LocalJobRunner' as 'local' galaxy.jobs DEBUG 2016-06-23 19:13:38,200 Legacy destination with id 'local:///', url 'local:///' converted, got params: galaxy.jobs.handler DEBUG 2016-06-23 19:13:38,200 Loaded job runners plugins: local galaxy.jobs.handler INFO 2016-06-23 19:13:38,200 job handler stop queue started galaxy.jobs.handler INFO 2016-06-23 19:13:38,222 job handler queue started ```] --- class: reduce70 ### Ignore this... .code[``` galaxy.sample_tracking.external_service_types DEBUG 2016-06-23 19:13:38,229 Loaded external_service_type: Simple unknown sequencer 1.0.0 galaxy.sample_tracking.external_service_types DEBUG 2016-06-23 19:13:38,230 Loaded external_service_type: Applied Biosystems SOLiD 1.0.0 ```] --- class: reduce90 ### Workflow Scheduler .code[``` galaxy.workflow.scheduling_manager DEBUG 2016-06-23 19:13:38,254 Starting workflow schedulers ```] --- class: reduce90 ### Controllers .code[``` galaxy.web.framework.base DEBUG 2016-06-23 19:13:38,347 Enabling 'external_service' controller, class: ExternalService galaxy.web.framework.base DEBUG 2016-06-23 19:13:38,347 Enabling 'requests_common' controller, class: RequestsCommon galaxy.web.framework.base DEBUG 2016-06-23 19:13:38,375 Enabling 'library_common' controller, class: LibraryCommon galaxy.web.framework.base DEBUG 2016-06-23 19:13:38,390 Enabling 'visualization' controller, class: VisualizationController galaxy.web.framework.base DEBUG 2016-06-23 19:13:38,398 Enabling 'page' controller, class: PageController galaxy.web.framework.base DEBUG 2016-06-23 19:13:38,400 Enabling 'async' controller, class: ASync ... galaxy.web.framework.base DEBUG 2016-06-23 19:13:38,728 Enabling 'history_content_tags' API controller, class: HistoryContentTagsController galaxy.web.framework.base DEBUG 2016-06-23 19:13:38,728 Enabling 'history_tags' API controller, class: HistoryTagsController galaxy.web.framework.base DEBUG 2016-06-23 19:13:38,728 Enabling 'workflow_tags' API controller, class: WorkflowTagsController ```] --- class: reduce90 ### Middleware .code[``` galaxy.webapps.galaxy.buildapp DEBUG 2016-06-23 19:13:39,036 Enabling 'httpexceptions' middleware galaxy.webapps.galaxy.buildapp DEBUG 2016-06-23 19:13:39,037 Enabling 'recursive' middleware galaxy.webapps.galaxy.buildapp DEBUG 2016-06-23 19:13:39,042 Enabling 'error' middleware galaxy.webapps.galaxy.buildapp DEBUG 2016-06-23 19:13:39,043 Enabling 'trans logger' middleware galaxy.webapps.galaxy.buildapp DEBUG 2016-06-23 19:13:39,044 Enabling 'x-forwarded-host' middleware galaxy.webapps.galaxy.buildapp DEBUG 2016-06-23 19:13:39,044 Enabling 'Request ID' middleware ```] --- class: reduce70 ### Static Paths for Viz .code[``` galaxy.webapps.galaxy.buildapp DEBUG 2016-06-23 19:13:39,048 added url, path to static middleware: /plugins/visualizations/charts/static, ./config/plugins/visualizations/charts/static galaxy.webapps.galaxy.buildapp DEBUG 2016-06-23 19:13:39,048 added url, path to static middleware: /plugins/visualizations/csg/static, ./config/plugins/visualizations/csg/static galaxy.webapps.galaxy.buildapp DEBUG 2016-06-23 19:13:39,049 added url, path to static middleware: /plugins/visualizations/graphviz/static, ./config/plugins/visualizations/graphviz/static galaxy.webapps.galaxy.buildapp DEBUG 2016-06-23 19:13:39,049 added url, path to static middleware: /plugins/visualizations/scatterplot/static, ./config/plugins/visualizations/scatterplot/static ```] --- class: reduce90 ### It is Up! .code[``` galaxy.queue_worker INFO 2016-06-23 19:13:39,049 Binding and starting galaxy control worker for main Starting server in PID 21102. serving on http://127.0.0.1:8080 ```] --- ## Production Galaxy - usegalaxy.org --- class: centered .pull-left[ #### Default SQLite Paste#http Single process Single host Local jobs ] .pull-right[ #### Production PostgreSQL uWSGI / nginx Multiple processes Multiple hosts Jobs across many clusters ] * https://usegalaxy.org/production * --- ### postgres - Database server can scale way beyond default sqlite - https://www.postgresql.org/ - github.com/galaxyproject/usegalaxy-playbook -> `roles/galaxyprojectdotorg.postgresql` --- ### nginx (or Apache) - Optimized servers for static content - https://www.nginx.com/resources/wiki/ - github.com/galaxyproject/usegalaxy-playbook -> `templates/nginx/usegalaxy.j2` --- ### Multi-processes Threads in Python are limited by the [GIL](https://wiki.python.org/moin/GlobalInterpreterLock). Running multiple processes of Galaxy and seperate processes for web handling and job processing works around this. This used to be an important detail - but uWSGI makes things a lot easier. --- ![Cluster Support](../../images/cluster_support.svg) ### Cluster Support --- ![usegalaxy.org web servers](../../images/usegalaxy_webservers.svg) --- ![usegalaxy.org servers](../../images/usegalaxyorg.svg) --- ## Q & A --- --- ### Legacy Client Architecture ??? Still some backbone and templates here and there, might be better to drop though? --- ![Client-Server Communications](../../images/server_client.plantuml.svg) ??? Workflow, Data Libraries, Visualization, History, Tool Menu, Many Grids, User and preference management. --- class: white ![Backbone MVC](../../images/backbone-model-view.svg) ### Backbone MVC --- ![Client-Server Communications (old)](../../images/server_client_old.plantuml.svg) ??? Admin things, Reports and Tool Shed Web app --- ![WSGI Application](../../images/wsgi_app.svg) ### Galaxy WSGI --- class: enlarge150 ### Why not just Django? We do build on many of the same standards, concepts, and libraries - the entire stack isn't custom code but there is a non-trivial web framework defined in "Galaxy". The Galaxy community likes Django and uses it to build newer webapps, Galaxy simply predates it and has evolved its own framework. --- ### <i class="fas fa-key" aria-hidden="true"></i><span class="visually-hidden">keypoints</span> Key points - Galaxy runs out of the box and fetches all needed dependencies. - Running Galaxy in production requires configuration. - The architecture is designed to be pluggable and extensible. - Learn more about different Galaxy aspects in our [development section](/topics/dev/). --- ## Thank You! This material is the result of a collaborative work. Thanks to the [Galaxy Training Network](https://training.galaxyproject.org) and all the contributors!
Authors:
John Chilton
Björn Grüning
Tutorial Content is licensed under
Creative Commons Attribution 4.0 International License
.