Epigenetics

DNA methylation is an epigenetic mechanism used by higher eukaryotes and involved in e.g. gene expression, X-Chromosome inactivating, imprinting, and gene silencing of germline specific gene and repetitive elements.

Requirements

Before diving into this topic, we recommend you to have a look at:

Material

You can view the tutorial materials in different languages by clicking the dropdown icon next to the slides () and tutorial () buttons below.
Lesson Slides Hands-on Recordings Input dataset Workflows
ATAC-Seq data analysis
CUT&RUN data analysis
DNA Methylation data analysis
Formation of the Super-Structures on the Inactive X
ChIP-seq
Hi-C analysis of Drosophila melanogaster cells using HiCExplorer
Identification of the binding sites of the T-cell acute lymphocytic leukemia protein 1 (TAL1)
ChIP-seq
Infinium Human Methylation BeadChip
Introduction to ChIP-Seq data analysis
Introduction to DNA Methylation data analysis

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Editorial Board

This material is reviewed by our Editorial Board:

orcid logoLucille Delisle avatar Lucille Delisleorcid logoFlorian Heyl avatar Florian HeylJoachim Wolff avatar Joachim Wolff

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Contributors

This material was contributed to by:

orcid logoHelena Rasche avatar Helena Rascheorcid logoPavankumar Videm avatar Pavankumar Videmorcid logoMartin Čech avatar Martin Čechorcid logoKatarzyna Kamieniecka avatar Katarzyna KamienieckaAnup Kumar avatar Anup Kumarorcid logoArmin Dadras avatar Armin Dadrasorcid logoBjörn Grüning avatar Björn Grüningorcid logoBérénice Batut avatar Bérénice Batutorcid logoWolfgang Maier avatar Wolfgang Maierorcid logoKrzysztof Poterlowicz avatar Krzysztof PoterlowiczFidel Ramirez avatar Fidel RamirezGildas Le Corguillé avatar Gildas Le CorguilléDevon Ryan avatar Devon Ryanorcid logoMo Heydarian avatar Mo Heydarianorcid logoMallory Freeberg avatar Mallory Freebergorcid logoNicola Soranzo avatar Nicola Soranzoorcid logoKhaled Jum'ah avatar Khaled Jum'ahVivek Bhardwaj avatar Vivek BhardwajEkaterina Polkh avatar Ekaterina Polkhorcid logoLucille Delisle avatar Lucille Delisleorcid logoSaskia Hiltemann avatar Saskia Hiltemannorcid logoYvan Le Bras avatar Yvan Le Brasorcid logoAnika Erxleben avatar Anika ErxlebenMehmet Tekman avatar Mehmet Tekmanorcid logoFlorian Heyl avatar Florian HeylLeily Rabbani avatar Leily RabbaniFriederike Dündar avatar Friederike DündarVerena Moosmann avatar Verena MoosmannJoachim Wolff avatar Joachim WolffTorsten Houwaart avatar Torsten HouwaartWilliam Durand avatar William DurandNiall Beard avatar Niall BeardMélanie Petera avatar Mélanie Peteraorcid logoMaria Doyle avatar Maria Doyle

Funding

These individuals or organisations provided funding support for the development of this resource

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de.NBI
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CRC992
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UFR
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ELIXIR Europe