Epigenetics

DNA methylation is an epigenetic mechanism used by higher eukaryotes and involved in e.g. gene expression, X-Chromosome inactivating, imprinting, and gene silencing of germline specific gene and repetitive elements.

Requirements

Before diving into this topic, we recommend you to have a look at:

Material

You can view the tutorial materials in different languages by clicking the dropdown icon next to the slides () and tutorial () buttons below.
Lesson Slides Hands-on Recordings Input dataset Workflows
ATAC-Seq data analysis
DNA Methylation data analysis
Formation of the Super-Structures on the Inactive X
ChIP-seq
Hi-C analysis of Drosophila melanogaster cells using HiCExplorer
Identification of the binding sites of the T-cell acute lymphocytic leukemia protein 1 (TAL1)
ChIP-seq
Infinium Human Methylation BeadChip
Introduction to ChIP-Seq data analysis
Introduction to DNA Methylation data analysis

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Editorial Board

This material is reviewed by our Editorial Board:

orcid logoLucille Delisle avatar Lucille Delisleorcid logoFlorian Heyl avatar Florian HeylJoachim Wolff avatar Joachim WolffDevon Ryan avatar Devon Ryan

Contributors

This material was contributed to by:

orcid logoMaria Doyle avatar Maria Doyleorcid logoKatarzyna Kamieniecka avatar Katarzyna Kamienieckaorcid logoMallory Freeberg avatar Mallory Freebergorcid logoKrzysztof Poterlowicz avatar Krzysztof PoterlowiczDevon Ryan avatar Devon Ryanorcid logoAnika Erxleben avatar Anika ErxlebenLeily Rabbani avatar Leily Rabbaniorcid logoMo Heydarian avatar Mo Heydarianorcid logoPavankumar Videm avatar Pavankumar VidemNiall Beard avatar Niall Beardorcid logoYvan Le Bras avatar Yvan Le Brasorcid logoBjörn Grüning avatar Björn Grüningorcid logoFlorian Heyl avatar Florian HeylJoachim Wolff avatar Joachim WolffMehmet Tekman avatar Mehmet TekmanEkaterina Polkh avatar Ekaterina Polkhorcid logoBérénice Batut avatar Bérénice Batutorcid logoNicola Soranzo avatar Nicola SoranzoMélanie Petera avatar Mélanie Peteraorcid logoKhaled Jum'ah avatar Khaled Jum'ahFidel Ramirez avatar Fidel Ramirezorcid logoLucille Delisle avatar Lucille Delisleorcid logoHelena Rasche avatar Helena RascheVivek Bhardwaj avatar Vivek Bhardwajorcid logoSaskia Hiltemann avatar Saskia HiltemannTorsten Houwaart avatar Torsten HouwaartAnup Kumar avatar Anup KumarFriederike Dündar avatar Friederike Dündar

Funding

These individuals or organisations provided funding support for the development of this resource

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UFR
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de.NBI
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ELIXIR Europe
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CRC992