Epigenetics

DNA methylation is an epigenetic mechanism used by higher eukaryotes and involved in e.g. gene expression, X-Chromosome inactivating, imprinting, and gene silencing of germline specific gene and repetitive elements.

Requirements

Before diving into this topic, we recommend you to have a look at:

Material

You can view the tutorial materials in different languages by clicking the dropdown icon next to the slides () and tutorial () buttons below.
Lesson Slides Hands-on Recordings Input dataset Workflows
ATAC-Seq data analysis
CUT&RUN data analysis
DNA Methylation data analysis
Formation of the Super-Structures on the Inactive X
ChIP-seq
Hi-C analysis of Drosophila melanogaster cells using HiCExplorer
Identification of the binding sites of the T-cell acute lymphocytic leukemia protein 1 (TAL1)
ChIP-seq
Infinium Human Methylation BeadChip
Introduction to ChIP-Seq data analysis
Introduction to DNA Methylation data analysis

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Editorial Board

This material is reviewed by our Editorial Board:

orcid logoLucille Delisle avatar Lucille Delisleorcid logoFlorian Heyl avatar Florian HeylJoachim Wolff avatar Joachim WolffDevon Ryan avatar Devon Ryan

Contributors

This material was contributed to by:

Anup Kumar avatar Anup KumarFriederike Dündar avatar Friederike Dündarorcid logoMallory Freeberg avatar Mallory FreebergEkaterina Polkh avatar Ekaterina PolkhVivek Bhardwaj avatar Vivek Bhardwajorcid logoMaria Doyle avatar Maria Doyleorcid logoFlorian Heyl avatar Florian HeylTorsten Houwaart avatar Torsten Houwaartorcid logoYvan Le Bras avatar Yvan Le Brasorcid logoKatarzyna Kamieniecka avatar Katarzyna Kamienieckaorcid logoBjörn Grüning avatar Björn Grüningorcid logoKrzysztof Poterlowicz avatar Krzysztof Poterlowiczorcid logoHelena Rasche avatar Helena RascheDevon Ryan avatar Devon Ryanorcid logoBérénice Batut avatar Bérénice BatutLeily Rabbani avatar Leily Rabbaniorcid logoNicola Soranzo avatar Nicola Soranzoorcid logoPavankumar Videm avatar Pavankumar VidemJoachim Wolff avatar Joachim Wolfforcid logoMo Heydarian avatar Mo HeydarianMehmet Tekman avatar Mehmet Tekmanorcid logoKhaled Jum'ah avatar Khaled Jum'ahFidel Ramirez avatar Fidel Ramirezorcid logoLucille Delisle avatar Lucille DelisleMélanie Petera avatar Mélanie PeteraNiall Beard avatar Niall Beardorcid logoSaskia Hiltemann avatar Saskia Hiltemannorcid logoAnika Erxleben avatar Anika Erxleben

Funding

These individuals or organisations provided funding support for the development of this resource

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CRC992
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de.NBI
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ELIXIR Europe
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UFR