Epigenetics

DNA methylation is an epigenetic mechanism used by higher eukaryotes and involved in e.g. gene expression, X-Chromosome inactivating, imprinting, and gene silencing of germline specific gene and repetitive elements.

Requirements

Before diving into this topic, we recommend you to have a look at:

Material

You can view the tutorial materials in different languages by clicking the dropdown icon next to the slides () and tutorial () buttons below.
Lesson Slides Hands-on Recordings Input dataset Workflows
ATAC-Seq data analysis
CUT&RUN data analysis
DNA Methylation data analysis
Formation of the Super-Structures on the Inactive X
ChIP-seq
Hi-C analysis of Drosophila melanogaster cells using HiCExplorer
Identification of the binding sites of the T-cell acute lymphocytic leukemia protein 1 (TAL1)
ChIP-seq
Infinium Human Methylation BeadChip
Introduction to ChIP-Seq data analysis
Introduction to DNA Methylation data analysis

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Editorial Board

This material is reviewed by our Editorial Board:

orcid logoLucille Delisle avatar Lucille Delisleorcid logoFlorian Heyl avatar Florian HeylJoachim Wolff avatar Joachim Wolff

Contributors

This material was contributed to by:

Joachim Wolff avatar Joachim Wolfforcid logoBérénice Batut avatar Bérénice BatutWilliam Durand avatar William DurandTorsten Houwaart avatar Torsten HouwaartDevon Ryan avatar Devon Ryanorcid logoKrzysztof Poterlowicz avatar Krzysztof Poterlowiczorcid logoWolfgang Maier avatar Wolfgang Maierorcid logoMaria Doyle avatar Maria Doyleorcid logoKhaled Jum'ah avatar Khaled Jum'ahorcid logoBjörn Grüning avatar Björn GrüningFriederike Dündar avatar Friederike Dündarorcid logoPavankumar Videm avatar Pavankumar VidemNiall Beard avatar Niall BeardMehmet Tekman avatar Mehmet TekmanEkaterina Polkh avatar Ekaterina PolkhVerena Moosmann avatar Verena Moosmannorcid logoFlorian Heyl avatar Florian HeylFidel Ramirez avatar Fidel Ramirezorcid logoArmin Dadras avatar Armin Dadrasorcid logoMo Heydarian avatar Mo Heydarianorcid logoMartin Čech avatar Martin ČechVivek Bhardwaj avatar Vivek BhardwajLeily Rabbani avatar Leily RabbaniMélanie Petera avatar Mélanie Peteraorcid logoHelena Rasche avatar Helena Rascheorcid logoMallory Freeberg avatar Mallory FreebergAnup Kumar avatar Anup Kumarorcid logoLucille Delisle avatar Lucille DelisleGildas Le Corguillé avatar Gildas Le Corguilléorcid logoNicola Soranzo avatar Nicola Soranzoorcid logoYvan Le Bras avatar Yvan Le Brasorcid logoSaskia Hiltemann avatar Saskia Hiltemannorcid logoAnika Erxleben avatar Anika Erxlebenorcid logoKatarzyna Kamieniecka avatar Katarzyna Kamieniecka

Funding

These individuals or organisations provided funding support for the development of this resource

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ELIXIR Europe
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CRC992
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de.NBI
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UFR