Epigenetics

DNA methylation is an epigenetic mechanism used by higher eukaryotes and involved in e.g. gene expression, X-Chromosome inactivating, imprinting, and gene silencing of germline specific gene and repetitive elements.

Requirements

Before diving into this topic, we recommend you to have a look at:

Material

You can view the tutorial materials in different languages by clicking the dropdown icon next to the slides () and tutorial () buttons below.
Lesson Slides Hands-on Recordings Input dataset Workflows
ATAC-Seq data analysis
CUT&RUN data analysis
DNA Methylation data analysis
Formation of the Super-Structures on the Inactive X
ChIP-seq
Hi-C analysis of Drosophila melanogaster cells using HiCExplorer
Identification of the binding sites of the T-cell acute lymphocytic leukemia protein 1 (TAL1)
ChIP-seq
Infinium Human Methylation BeadChip
Introduction to ChIP-Seq data analysis
Introduction to DNA Methylation data analysis

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Editorial Board

This material is reviewed by our Editorial Board:

orcid logoLucille Delisle avatar Lucille Delisleorcid logoFlorian Heyl avatar Florian HeylJoachim Wolff avatar Joachim Wolff

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Contributors

This material was contributed to by:

Verena Moosmann avatar Verena Moosmannorcid logoMartin Čech avatar Martin Čechorcid logoKatarzyna Kamieniecka avatar Katarzyna Kamienieckaorcid logoBjörn Grüning avatar Björn GrüningMehmet Tekman avatar Mehmet Tekmanorcid logoKhaled Jum'ah avatar Khaled Jum'ahorcid logoYvan Le Bras avatar Yvan Le Brasorcid logoMaria Doyle avatar Maria DoyleDevon Ryan avatar Devon RyanLeily Rabbani avatar Leily Rabbaniorcid logoKrzysztof Poterlowicz avatar Krzysztof Poterlowiczorcid logoNicola Soranzo avatar Nicola SoranzoTorsten Houwaart avatar Torsten HouwaartVivek Bhardwaj avatar Vivek BhardwajNiall Beard avatar Niall BeardGildas Le Corguillé avatar Gildas Le Corguilléorcid logoWolfgang Maier avatar Wolfgang Maierorcid logoAnika Erxleben avatar Anika ErxlebenMélanie Petera avatar Mélanie Peteraorcid logoBérénice Batut avatar Bérénice Batutorcid logoHelena Rasche avatar Helena RascheFidel Ramirez avatar Fidel RamirezEkaterina Polkh avatar Ekaterina PolkhJoachim Wolff avatar Joachim Wolfforcid logoLucille Delisle avatar Lucille Delisleorcid logoMallory Freeberg avatar Mallory Freebergorcid logoTristan Reynolds avatar Tristan ReynoldsWilliam Durand avatar William DurandFriederike Dündar avatar Friederike DündarAnup Kumar avatar Anup Kumarorcid logoPavankumar Videm avatar Pavankumar Videmorcid logoArmin Dadras avatar Armin Dadrasorcid logoMo Heydarian avatar Mo Heydarianorcid logoFlorian Heyl avatar Florian Heylorcid logoSaskia Hiltemann avatar Saskia Hiltemann

Funding

These individuals or organisations provided funding support for the development of this resource

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de.NBI
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UFR
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Australian BioCommons
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CRC992
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The University of Melbourne
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Melbourne Bioinformatics
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ELIXIR Europe