Epigenetics

DNA methylation is an epigenetic mechanism used by higher eukaryotes and involved in e.g. gene expression, X-Chromosome inactivating, imprinting, and gene silencing of germline specific gene and repetitive elements.

Requirements

Before diving into this topic, we recommend you to have a look at:

Material

You can view the tutorial materials in different languages by clicking the dropdown icon next to the slides () and tutorial () buttons below.
Lesson Slides Hands-on Recordings Input dataset Workflows
ATAC-Seq data analysis
CUT&RUN data analysis
DNA Methylation data analysis
Formation of the Super-Structures on the Inactive X
ChIP-seq
Hi-C analysis of Drosophila melanogaster cells using HiCExplorer
Identification of the binding sites of the T-cell acute lymphocytic leukemia protein 1 (TAL1)
ChIP-seq
Infinium Human Methylation BeadChip
Introduction to ChIP-Seq data analysis
Introduction to DNA Methylation data analysis

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Editorial Board

This material is reviewed by our Editorial Board:

orcid logoLucille Delisle avatar Lucille Delisleorcid logoFlorian Heyl avatar Florian HeylJoachim Wolff avatar Joachim Wolff

Contributors

This material was contributed to by:

orcid logoPavankumar Videm avatar Pavankumar Videmorcid logoYvan Le Bras avatar Yvan Le BrasDevon Ryan avatar Devon RyanLeily Rabbani avatar Leily Rabbaniorcid logoNicola Soranzo avatar Nicola Soranzoorcid logoHelena Rasche avatar Helena Rascheorcid logoFlorian Heyl avatar Florian Heylorcid logoWolfgang Maier avatar Wolfgang Maierorcid logoKrzysztof Poterlowicz avatar Krzysztof PoterlowiczAnup Kumar avatar Anup Kumarorcid logoBjörn Grüning avatar Björn GrüningEkaterina Polkh avatar Ekaterina Polkhorcid logoMaria Doyle avatar Maria DoyleFidel Ramirez avatar Fidel Ramirezorcid logoMallory Freeberg avatar Mallory FreebergVivek Bhardwaj avatar Vivek Bhardwajorcid logoBérénice Batut avatar Bérénice BatutMehmet Tekman avatar Mehmet TekmanFriederike Dündar avatar Friederike Dündarorcid logoMo Heydarian avatar Mo HeydarianTorsten Houwaart avatar Torsten HouwaartJoachim Wolff avatar Joachim Wolfforcid logoSaskia Hiltemann avatar Saskia Hiltemannorcid logoAnika Erxleben avatar Anika Erxlebenorcid logoKatarzyna Kamieniecka avatar Katarzyna KamienieckaNiall Beard avatar Niall BeardMélanie Petera avatar Mélanie Peteraorcid logoLucille Delisle avatar Lucille Delisleorcid logoKhaled Jum'ah avatar Khaled Jum'ah

Funding

These individuals or organisations provided funding support for the development of this resource

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de.NBI
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CRC992
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ELIXIR Europe
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UFR