Epigenetics

DNA methylation is an epigenetic mechanism used by higher eukaryotes and involved in e.g. gene expression, X-Chromosome inactivating, imprinting, and gene silencing of germline specific gene and repetitive elements.

Requirements

Before diving into this topic, we recommend you to have a look at:

Material

You can view the tutorial materials in different languages by clicking the dropdown icon next to the slides () and tutorial () buttons below.
Lesson Slides Hands-on Recordings Input dataset Workflows
ATAC-Seq data analysis
CUT&RUN data analysis
DNA Methylation data analysis
Formation of the Super-Structures on the Inactive X
ChIP-seq
Hi-C analysis of Drosophila melanogaster cells using HiCExplorer
Identification of the binding sites of the T-cell acute lymphocytic leukemia protein 1 (TAL1)
ChIP-seq
Infinium Human Methylation BeadChip
Introduction to ChIP-Seq data analysis
Introduction to DNA Methylation data analysis

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Editorial Board

This material is reviewed by our Editorial Board:

orcid logoLucille Delisle avatar Lucille Delisleorcid logoFlorian Heyl avatar Florian HeylJoachim Wolff avatar Joachim Wolff

Contributors

This material was contributed to by:

Mehmet Tekman avatar Mehmet TekmanAnup Kumar avatar Anup KumarFriederike Dündar avatar Friederike Dündarorcid logoBjörn Grüning avatar Björn Grüningorcid logoKhaled Jum'ah avatar Khaled Jum'ahEkaterina Polkh avatar Ekaterina Polkhorcid logoLucille Delisle avatar Lucille Delisleorcid logoKrzysztof Poterlowicz avatar Krzysztof PoterlowiczMélanie Petera avatar Mélanie Peteraorcid logoPavankumar Videm avatar Pavankumar Videmorcid logoArmin Dadras avatar Armin DadrasTorsten Houwaart avatar Torsten Houwaartorcid logoHelena Rasche avatar Helena Rascheorcid logoAnika Erxleben avatar Anika Erxlebenorcid logoKatarzyna Kamieniecka avatar Katarzyna Kamienieckaorcid logoMaria Doyle avatar Maria Doyleorcid logoSaskia Hiltemann avatar Saskia Hiltemannorcid logoNicola Soranzo avatar Nicola SoranzoDevon Ryan avatar Devon Ryanorcid logoBérénice Batut avatar Bérénice BatutNiall Beard avatar Niall Beardorcid logoMallory Freeberg avatar Mallory FreebergGildas Le Corguillé avatar Gildas Le Corguilléorcid logoFlorian Heyl avatar Florian HeylVivek Bhardwaj avatar Vivek BhardwajFidel Ramirez avatar Fidel Ramirezorcid logoMo Heydarian avatar Mo HeydarianWilliam Durand avatar William DurandVerena Moosmann avatar Verena Moosmannorcid logoWolfgang Maier avatar Wolfgang MaierLeily Rabbani avatar Leily RabbaniJoachim Wolff avatar Joachim Wolfforcid logoYvan Le Bras avatar Yvan Le Brasorcid logoMartin Čech avatar Martin Čech

Funding

These individuals or organisations provided funding support for the development of this resource

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de.NBI
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UFR
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CRC992
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ELIXIR Europe