Epigenetics

DNA methylation is an epigenetic mechanism used by higher eukaryotes and involved in e.g. gene expression, X-Chromosome inactivating, imprinting, and gene silencing of germline specific gene and repetitive elements.

Requirements

Before diving into this topic, we recommend you to have a look at:

Material

You can view the tutorial materials in different languages by clicking the dropdown icon next to the slides () and tutorial () buttons below.
Lesson Slides Hands-on Recordings Input dataset Workflows
ATAC-Seq data analysis
DNA Methylation data analysis
Formation of the Super-Structures on the Inactive X
ChIP-seq
Hi-C analysis of Drosophila melanogaster cells using HiCExplorer
Identification of the binding sites of the T-cell acute lymphocytic leukemia protein 1 (TAL1)
ChIP-seq
Infinium Human Methylation BeadChip
Introduction to ChIP-Seq data analysis
Introduction to DNA Methylation data analysis

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Editorial Board

This material is reviewed by our Editorial Board:

orcid logoLucille Delisle avatar Lucille Delisleorcid logoFlorian Heyl avatar Florian HeylJoachim Wolff avatar Joachim WolffDevon Ryan avatar Devon Ryan

Contributors

This material was contributed to by:

orcid logoNicola Soranzo avatar Nicola SoranzoEkaterina Polkh avatar Ekaterina PolkhDevon Ryan avatar Devon RyanMélanie Petera avatar Mélanie Peteraorcid logoMaria Doyle avatar Maria Doyleorcid logoSaskia Hiltemann avatar Saskia Hiltemannorcid logoMo Heydarian avatar Mo Heydarianorcid logoFlorian Heyl avatar Florian Heylorcid logoMallory Freeberg avatar Mallory Freebergorcid logoBérénice Batut avatar Bérénice Batutorcid logoKatarzyna Kamieniecka avatar Katarzyna KamienieckaAnup Kumar avatar Anup KumarMehmet Tekman avatar Mehmet Tekmanorcid logoPavankumar Videm avatar Pavankumar VidemNiall Beard avatar Niall Beardorcid logoHelena Rasche avatar Helena Rascheorcid logoKrzysztof Poterlowicz avatar Krzysztof PoterlowiczFidel Ramirez avatar Fidel Ramirezorcid logoKhaled Jum'ah avatar Khaled Jum'ahFriederike Dündar avatar Friederike DündarJoachim Wolff avatar Joachim Wolfforcid logoYvan Le Bras avatar Yvan Le BrasTorsten Houwaart avatar Torsten Houwaartorcid logoLucille Delisle avatar Lucille DelisleLeily Rabbani avatar Leily Rabbaniorcid logoBjörn Grüning avatar Björn GrüningVivek Bhardwaj avatar Vivek Bhardwajorcid logoAnika Erxleben avatar Anika Erxleben

Funding

These individuals or organisations provided funding support for the development of this resource

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UFR
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ELIXIR Europe
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CRC992
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de.NBI